INT305311

Context Info Confidence 0.45 First Reported 2010 Last Reported 2010 Negated 0 Speculated 0 Reported most in Body Documents 1 Total Number 2 Disease Relevance 0.21 Pain Relevance 0

extracellular space (Serpina5) extracellular region (Serpina5) protein complex (Serpina5)

Anatomy Link Frequency lungs 2 tubules 2 Serpina5 (Mus musculus)

Pain Link Frequency Relevance Heat alcohol 6 7.96 Bile 4 5.00 anesthesia 2 5.00

Disease Link Frequency Relevance Heat Stress Incontinence 10 86.68 Hypertrophy 2 64.76 Cancer 2 42.72 Corneal Neovascularization 2 36.64 Apoptosis 14 5.00 Hypersensitivity 6 5.00 Sprains And Strains 4 5.00 Thrombosis 2 5.00 Thrombosis Related Under Development 2 5.00 Hypertension 2 5.00

Sentences Mentioned In

Key:

Protein

Mutation

Event

Anatomy

Negation

Speculation

Pain term

Disease term

PCI expression ceases in the perinatal period and is undetectable in adult lungs.

Regulation (undetectable) of Gene_expression (expression) of PCI in lungs

1) Confidence 0.45 Published 2010 Journal J Mol Histol Section Body Doc Link PMC2852590 Disease Relevance 0.06 Pain Relevance 0

In situ hybridization (b, c, e, g, i) and immunohistochemistry (a, d, f, h, j) on formaldehyde fixed paraffin sections. a Early expression of PCI in myocytes of the heart at ED 9.5; b PCI positive cells in choroid plexus (arrowheads) in the lateral ventricle of the brain; c skin of upper and lower jaws; d PCI in myocardium at ED 11.5; note absence of staining in non-myocardial cells including the cushion material of the atrioventricular canal and the developing valves in the outflow tract; e, presence of PCI in oesophagus and lung and absence in trachea; f, g pseudoglandular stage of lung development; note presence of PCI in distal tubules whereas proximal tubules are devoid of staining (asterisks); h, i PCI in cardiac region of stomach where the PCI-positive oesophagus enters (arrow) and in gonad; j PCI expression in hindgut, urethra and skin of anal bay.

Regulation (presence) of Gene_expression (expression) of PCI in tubules associated with stress incontinence

2) Confidence 0.24 Published 2010 Journal J Mol Histol Section Body Doc Link PMC2852590 Disease Relevance 0.14 Pain Relevance 0

General Comments

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