INT305322

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Context Info
Confidence 0.06
First Reported 2010
Last Reported 2010
Negated 1
Speculated 1
Reported most in Body
Documents 1
Total Number 2
Disease Relevance 1.20
Pain Relevance 0.16

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

Anatomy Link Frequency
body 1
Olfr927-ps1 (Mus musculus)
Pain Link Frequency Relevance Heat
diabetic neuropathy 14 97.76 Very High Very High Very High
Kinase C 2 59.68 Quite High
Spinal cord 28 41.44 Quite Low
Sciatic nerve 24 37.68 Quite Low
Peripheral nervous system 12 30.84 Quite Low
Inflammation 10 25.36 Quite Low
hypoalgesia 14 10.48 Low Low
tail-flick 12 7.20 Low Low
withdrawal 20 5.00 Very Low Very Low Very Low
Brush evoked pain 8 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Body Weight 20 99.96 Very High Very High Very High
Disease 4 98.00 Very High Very High Very High
Diabetic Neuropathy 14 97.76 Very High Very High Very High
Stress 26 92.00 High High
Metabolic Syndrome 18 86.72 High High
Prediabetic State 12 85.80 High High
Neuropathic Pain 48 84.68 Quite High
Hyperglycemia 12 65.68 Quite High
Diabetes Mellitus 34 53.88 Quite High
Diabetes Complications 2 53.08 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Further studies are needed to determine whether PMI-5011 treatment is effective against functional and structural deficits of advanced diabetic neuropathy.



Spec (whether) Regulation (effective) of PMI-5011 associated with diabetic neuropathy
1) Confidence 0.06 Published 2010 Journal Mediators of Inflammation Section Body Doc Link PMC2852597 Disease Relevance 0.87 Pain Relevance 0.16
A 7-week PMI-5011 treatment did not affect body weights in either NC- or HFD-fed mice.
Neg (not) Regulation (affect) of PMI-5011 in body associated with body weight
2) Confidence 0.06 Published 2010 Journal Mediators of Inflammation Section Body Doc Link PMC2852597 Disease Relevance 0.33 Pain Relevance 0

General Comments

This test has worked.

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