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Context Info
Confidence 0.25
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 2.22
Pain Relevance 0

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

DNA binding (Msh6)
Anatomy Link Frequency
MLH1 2
Msh6 (Mus musculus)
Pain Link Frequency Relevance Heat
palliative 1 5.00 Very Low Very Low Very Low
addiction 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Endometroid Carcinoma 12 99.68 Very High Very High Very High
Microsatellite Instability 15 98.96 Very High Very High Very High
Cancer 60 93.12 High High
Aneuploidy 3 86.32 High High
Endometrial Cancer 67 83.12 Quite High
Genomic Instability 5 69.84 Quite High
Colon Cancer 5 67.12 Quite High
Carcinoma 9 48.40 Quite Low
Clear Cell Adenocarcinoma 1 43.36 Quite Low
Apoptosis 4 23.84 Low Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Inactivation of the mismatch repair gene MLH1 by methylation of the promoter seems to be the most frequent cause of MI in sporadic endometrioid carcinomas, followed by a loss of the expression of other two mismatch repair genes, the MSH2 and MSH6 genes.
Negative_regulation (loss) of Gene_expression (expression) of MSH6 in MLH1 associated with endometroid carcinoma and microsatellite instability
1) Confidence 0.25 Published 2010 Journal Obstetrics and Gynecology International Section Body Doc Link PMC2852605 Disease Relevance 2.22 Pain Relevance 0

General Comments

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