INT305348

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Context Info
Confidence 0.25
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 2
Total Number 2
Disease Relevance 2.36
Pain Relevance 0.31

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

nucleus (Peg3) intracellular (Peg3) cytoplasm (Peg3)
Peg3 (Mus musculus)
Pain Link Frequency Relevance Heat
Bile 11 87.72 High High
fibrosis 58 81.32 Quite High
Inflammation 60 65.32 Quite High
corticosteroid 1 5.00 Very Low Very Low Very Low
palliative 1 5.00 Very Low Very Low Very Low
cINOD 1 5.00 Very Low Very Low Very Low
Inflammatory response 1 5.00 Very Low Very Low Very Low
addiction 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Disease 27 98.08 Very High Very High Very High
Endometrial Cancer 67 97.28 Very High Very High Very High
Biliary Atresia 19 94.44 High High
Gallstones 3 87.08 High High
Fibrosis 58 83.84 Quite High
Cancer 60 81.52 Quite High
Apoptosis 4 76.96 Quite High
Injury 8 75.60 Quite High
Carcinoma In Situ 5 66.72 Quite High
INFLAMMATION 62 65.32 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
For example, among the genes with unique expression patterns were five imprinted genes (Igf2, Peg3, Peg10, Meg3, and IPW) in infants with the embryonic form, suggesting that a failure to down-regulate embryonic gene programs may be involved in the non-hepatic malformations that are typical of this group of patients [23].
Gene_expression (expression) of Peg3
1) Confidence 0.25 Published 2010 Journal Genome Med Section Body Doc Link PMC2887077 Disease Relevance 1.16 Pain Relevance 0.31
Other genes inactivated by promoter hypermethylation in endometrial cancer include PgR [69], the cell cycle control genes 14-3-3 sigma [70], homeobox gene HOXA11, thrombospondin-2 gene (THBS2) [71], paternally expressed gene 3 (PEG3) [72], as well as the detoxifying enzyme glutathione S-transferase P1 (GSTP1) [73].
Gene_expression (expressed) of PEG3 associated with endometrial cancer
2) Confidence 0.23 Published 2010 Journal Obstetrics and Gynecology International Section Body Doc Link PMC2852605 Disease Relevance 1.20 Pain Relevance 0

General Comments

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