INT305533

From wiki-pain
Jump to: navigation, search
Context Info
Confidence 0.03
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 2
Disease Relevance 0.28
Pain Relevance 0.19

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

extracellular space (Il3) extracellular region (Il3) nucleus (Runx1)
DNA binding (Runx1) transcription factor binding (Runx1)
Anatomy Link Frequency
hematopoietic progenitor cells 1
Runx1 (Mus musculus)
Il3 (Mus musculus)
Pain Link Frequency Relevance Heat
Neuropathic pain 36 82.40 Quite High
Calcitonin gene-related peptide 2 80.40 Quite High
Neuropeptide 2 79.12 Quite High
Peripheral nervous system 2 57.28 Quite High
withdrawal 14 7.76 Low Low
Eae 10 5.00 Very Low Very Low Very Low
Sciatic nerve 8 5.00 Very Low Very Low Very Low
Spinal cord 6 5.00 Very Low Very Low Very Low
nociceptor 4 5.00 Very Low Very Low Very Low
Peripheral nerve injury 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Neuropathic Pain 38 82.40 Quite High
Repression 2 78.32 Quite High
Neurodegenerative Disease 2 61.12 Quite High
Targeted Disruption 26 60.80 Quite High
Nociception 4 50.00 Quite Low
Hypersensitivity 10 46.96 Quite Low
Injury 24 5.00 Very Low Very Low Very Low
Megacolon 12 5.00 Very Low Very Low Very Low
Nervous System Injury 4 5.00 Very Low Very Low Very Low
Sprains And Strains 2 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Runx1a was shown to transactivate the human interleukin-3 promoter, albeit with less efficiency than Runx1b (long isoform) (5).
Runx1a Positive_regulation (transactivate) of interleukin-3 promoter
1) Confidence 0.03 Published 2010 Journal Upsala Journal of Medical Sciences Section Body Doc Link PMC2853355 Disease Relevance 0.06 Pain Relevance 0
However, Runx1a may also have specific effects of its own, as evidenced by its ability to transactivate the interleukin-3 promoter (5) and enhance engraftment capacity of hematopoietic progenitor cells (6).
Runx1a Positive_regulation (transactivate) of interleukin-3 promoter in hematopoietic progenitor cells
2) Confidence 0.03 Published 2010 Journal Upsala Journal of Medical Sciences Section Body Doc Link PMC2853355 Disease Relevance 0.22 Pain Relevance 0.19

General Comments

This test has worked.

Personal tools
Namespaces

Variants
Actions
Navigation
Toolbox