INT305535

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Context Info
Confidence 0.41
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 2
Disease Relevance 0.70
Pain Relevance 0.10

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytosol (HPRT1) small molecule metabolic process (HPRT1) transferase activity, transferring glycosyl groups (HPRT1)
nucleus (Runx1) DNA binding (Runx1) transcription factor binding (Runx1)
HPRT1 (Homo sapiens)
Runx1 (Mus musculus)
Pain Link Frequency Relevance Heat
Neuropathic pain 36 52.04 Quite High
Calcitonin gene-related peptide 2 18.16 Low Low
Neuropeptide 2 16.88 Low Low
withdrawal 14 5.00 Very Low Very Low Very Low
Eae 10 5.00 Very Low Very Low Very Low
Sciatic nerve 8 5.00 Very Low Very Low Very Low
Spinal cord 6 5.00 Very Low Very Low Very Low
nociceptor 4 5.00 Very Low Very Low Very Low
Peripheral nerve injury 2 5.00 Very Low Very Low Very Low
Peripheral nervous system 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Sprains And Strains 2 93.76 High High
Targeted Disruption 26 80.12 Quite High
Neuropathic Pain 38 52.04 Quite High
Repression 2 16.08 Low Low
Injury 24 9.12 Low Low
Megacolon 12 5.00 Very Low Very Low Very Low
Hypersensitivity 10 5.00 Very Low Very Low Very Low
Nervous System Injury 4 5.00 Very Low Very Low Very Low
Nociception 4 5.00 Very Low Very Low Very Low
Congenital Anomalies 2 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
RtTA was targeted into the ubiquitously expressed Rosa26 locus, or Sox10 locus, and Runx1a-IRES-EGFP cDNA driven by the tetracycline-responsive element (TRE) targeted upstream the hypoxanthine phosphoribosyltransferase (HPRT) locus.
hypoxanthine phosphoribosyltransferase Binding (targeted) of Runx1a
1) Confidence 0.41 Published 2010 Journal Upsala Journal of Medical Sciences Section Body Doc Link PMC2853355 Disease Relevance 0.35 Pain Relevance 0.05
RtTA was targeted into the ubiquitously expressed Rosa26 locus, or Sox10 locus, and Runx1a-IRES-EGFP cDNA driven by the tetracycline-responsive element (TRE) targeted upstream the hypoxanthine phosphoribosyltransferase (HPRT) locus.
HPRT Binding (targeted) of Runx1a
2) Confidence 0.41 Published 2010 Journal Upsala Journal of Medical Sciences Section Body Doc Link PMC2853355 Disease Relevance 0.35 Pain Relevance 0.05

General Comments

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