INT305547

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Context Info
Confidence 0.00
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 2
Total Number 2
Disease Relevance 1.83
Pain Relevance 0.48

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

intracellular (Gtf3a) DNA binding (Gtf3a) cytoplasm (VEGFA)
extracellular space (VEGFA) extracellular region (VEGFA) growth (VEGFA)
VEGFA (Homo sapiens)
Gtf3a (Mus musculus)
Pain Link Frequency Relevance Heat
ischemia 33 99.16 Very High Very High Very High
cytokine 9 92.04 High High
Inflammation 33 80.48 Quite High
cINOD 5 62.88 Quite High
Inflammatory response 1 61.84 Quite High
fibrosis 3 5.00 Very Low Very Low Very Low
ketamine 1 5.00 Very Low Very Low Very Low
anesthesia 1 5.00 Very Low Very Low Very Low
chemokine 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Cv Unclassified Under Development 33 99.16 Very High Very High Very High
Cancer 18 97.20 Very High Very High Very High
Necrosis 12 96.52 Very High Very High Very High
Hodgkin's Disease 22 91.68 High High
INFLAMMATION 36 80.48 Quite High
Cardiovascular Disease 1 75.36 Quite High
Hematologic Neoplasms 2 72.04 Quite High
Brain Tumor 1 56.12 Quite High
Adenocarcinoma 2 55.44 Quite High
Fever 1 51.04 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
VEGF induces angiogenesis by stimulating EC migration and proliferation primarily through the VEGF type2 receptor (VEGFR2) [8], as well as by upregulating stromal derived factor-1?
VEGF Positive_regulation (upregulating) of factor
1) Confidence 0.00 Published 2010 Journal PLoS ONE Section Body Doc Link PMC2955540 Disease Relevance 0.80 Pain Relevance 0.36
It is emphasized that cox-2 increases the expression of angiogenic factors such as PGE2, as well as the expression of proangiogenic factors; and also that PGE2 is a strong vascular endothelial growth factor (VEGF) inducer and consequently cox-2 contributes to angiogenesis and increases the tumor proliferation [7,13,22].
VEGF Positive_regulation (inducer) of factor associated with cancer
2) Confidence 0.00 Published 2010 Journal Diagn Pathol Section Body Doc Link PMC2853498 Disease Relevance 1.04 Pain Relevance 0.12

General Comments

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