INT305623

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Context Info
Confidence 0.00
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.27
Pain Relevance 0.27

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytoplasm (Ca2, Cabin1) cytosol (Ca2) extracellular space (Ca2)
lyase activity (Ca2) nucleolus (Cabin1) nucleus (Cabin1)
Ca2 (Rattus norvegicus)
Cabin1 (Rattus norvegicus)
Pain Link Frequency Relevance Heat
depression 9 95.86 Very High Very High Very High
long-term potentiation 12 95.70 Very High Very High Very High
imagery 27 9.48 Low Low
Glutamate receptor 5 5.00 Very Low Very Low Very Low
Neurotransmitter 4 5.00 Very Low Very Low Very Low
potassium channel 2 5.00 Very Low Very Low Very Low
tetrodotoxin 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Depression 9 95.86 Very High Very High Very High
Alzheimer's Dementia 5 50.00 Quite Low
Disease 9 5.00 Very Low Very Low Very Low
Death 2 5.00 Very Low Very Low Very Low
Cognitive Disorder 2 5.00 Very Low Very Low Very Low
Amyloid Plaque 2 5.00 Very Low Very Low Very Low
Toxicity 1 5.00 Very Low Very Low Very Low
Apoptosis 1 5.00 Very Low Very Low Very Low
Congenital Anomalies 1 5.00 Very Low Very Low Very Low
Amnesia 1 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
In particular, both LTP and LTD depend on Ca2+ signaling to control synaptic receptor trafficking: the former requires a high Ca2+ elevation for activating CaMKII and downstream effectors for AMPA insertion whereas the latter needs small Ca2+ signals to activate calcineurin phosphatase for AMAPR removal from the surface [20,49,50].
Ca2 Positive_regulation (activate) of calcineurin associated with depression and long-term potentiation
1) Confidence 0.00 Published 2010 Journal Mol Brain Section Body Doc Link PMC2853530 Disease Relevance 0.27 Pain Relevance 0.27

General Comments

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