INT305734

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Context Info
Confidence 0.01
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Abstract
Documents 1
Total Number 2
Disease Relevance 0.50
Pain Relevance 1.08

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

transport (Sort1, Trpv1) plasma membrane (Sort1, Trpv1) cell differentiation (Sort1)
endosome (Sort1) Golgi apparatus (Sort1) endoplasmic reticulum (Sort1)
Anatomy Link Frequency
neurons 2
Sort1 (Mus musculus)
Trpv1 (Mus musculus)
Pain Link Frequency Relevance Heat
antidepressant 132 92.80 High High
depression 68 88.64 High High
antagonist 8 84.60 Quite High
potassium channel 12 81.48 Quite High
Pyramidal cell 8 68.96 Quite High
Raphe 8 57.04 Quite High
fluoxetine 32 25.00 Low Low
sSRI 18 25.00 Low Low
Onset of action 6 25.00 Low Low
Hippocampus 18 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Depression 68 88.64 High High
Neurodegenerative Disease 32 29.76 Quite Low
Anxiety Disorder 26 5.00 Very Low Very Low Very Low
Stress 14 5.00 Very Low Very Low Very Low
Disease 6 5.00 Very Low Very Low Very Low
Shock 6 5.00 Very Low Very Low Very Low
Body Weight 4 5.00 Very Low Very Low Very Low
Death 4 5.00 Very Low Very Low Very Low
Injury 4 5.00 Very Low Very Low Very Low
Decapitation 2 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
NTSR3/Sortilin interacted with the TREK-1 channel, as shown by immunoprecipitation of TREK-1 and NTSR3/Sortilin from COS-7 cells and cortical neurons co-expressing both proteins.
NTSR3 Binding (interacted) of channel in neurons
1) Confidence 0.01 Published 2010 Journal PLoS Biology Section Abstract Doc Link PMC2854129 Disease Relevance 0.25 Pain Relevance 0.54
NTSR3/Sortilin interacted with the TREK-1 channel, as shown by immunoprecipitation of TREK-1 and NTSR3/Sortilin from COS-7 cells and cortical neurons co-expressing both proteins.
Sortilin Binding (interacted) of channel in neurons
2) Confidence 0.01 Published 2010 Journal PLoS Biology Section Abstract Doc Link PMC2854129 Disease Relevance 0.25 Pain Relevance 0.54

General Comments

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