INT305737

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Context Info
Confidence 0.19
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 2
Disease Relevance 0.11
Pain Relevance 0.06

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

endosome (Sort1, Gga2) transport (Sort1, Gga2) Golgi apparatus (Sort1, Gga2)
cell differentiation (Sort1) endoplasmic reticulum (Sort1) intracellular (Gga2)
Anatomy Link Frequency
ear 2
Sort1 (Mus musculus)
Gga2 (Mus musculus)
Pain Link Frequency Relevance Heat
antidepressant 132 55.20 Quite High
depression 68 48.92 Quite Low
amygdala 4 33.20 Quite Low
Hippocampus 18 32.40 Quite Low
Nucleus accumbens 4 31.36 Quite Low
Raphe 8 29.28 Quite Low
sSRI 18 26.92 Quite Low
fluoxetine 32 5.00 Very Low Very Low Very Low
potassium channel 12 5.00 Very Low Very Low Very Low
antagonist 8 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Death 4 54.24 Quite High
Depression 68 48.92 Quite Low
Neurodegenerative Disease 32 18.28 Low Low
Stress 14 17.08 Low Low
Anxiety Disorder 26 5.00 Very Low Very Low Very Low
Disease 6 5.00 Very Low Very Low Very Low
Shock 6 5.00 Very Low Very Low Very Low
Body Weight 4 5.00 Very Low Very Low Very Low
Injury 4 5.00 Very Low Very Low Very Low
Decapitation 2 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Indeed, the C-terminus of NTSR3/Sortilin interacts with the VHS domain of the sorting protein GGA2 (Golgi-localizing, g-adaptin ear homology domain, ADP-ribosylation factor-binding protein) [10].
NTSR3 Binding (interacts) of GGA2 in ear
1) Confidence 0.19 Published 2010 Journal PLoS Biology Section Body Doc Link PMC2854129 Disease Relevance 0.05 Pain Relevance 0.03
Indeed, the C-terminus of NTSR3/Sortilin interacts with the VHS domain of the sorting protein GGA2 (Golgi-localizing, g-adaptin ear homology domain, ADP-ribosylation factor-binding protein) [10].
Sortilin Binding (interacts) of GGA2 in ear
2) Confidence 0.17 Published 2010 Journal PLoS Biology Section Body Doc Link PMC2854129 Disease Relevance 0.05 Pain Relevance 0.03

General Comments

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