INT305799

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Context Info
Confidence 0.00
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 6
Disease Relevance 0.76
Pain Relevance 0.26

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

LRCH2 (Homo sapiens)
OxP-11D (Mus musculus)
Pain Link Frequency Relevance Heat
Inflammation 120 97.24 Very High Very High Very High
Inflammatory response 12 5.00 Very Low Very Low Very Low
anesthesia 6 5.00 Very Low Very Low Very Low
rheumatoid arthritis 6 5.00 Very Low Very Low Very Low
isoflurane 6 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
INFLAMMATION 126 97.24 Very High Very High Very High
Hemolysis 12 86.48 High High
Atherosclerosis 30 67.32 Quite High
Disorder Of Lipid Metabolism 30 5.00 Very Low Very Low Very Low
Cardiovascular Disease 24 5.00 Very Low Very Low Very Low
Diabetes Mellitus 6 5.00 Very Low Very Low Very Low
Pathologic Processes 6 5.00 Very Low Very Low Very Low
Disease 6 5.00 Very Low Very Low Very Low
Cancer 6 5.00 Very Low Very Low Very Low
Colitis 6 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Similarly, OxP-11D bound 13(S)-HODE (hydroxyoctadecadienoic acid) with higher affinity than D-4F, yet D-4F had greater affinity for 9(S)-HODE.
D-4F Binding (bound) of OxP-11D
1) Confidence 0.00 Published 2010 Journal PLoS ONE Section Body Doc Link PMC2854715 Disease Relevance 0 Pain Relevance 0
Similarly, OxP-11D bound 13(S)-HODE (hydroxyoctadecadienoic acid) with higher affinity than D-4F, yet D-4F had greater affinity for 9(S)-HODE.
D-4F Binding (bound) of OxP-11D
2) Confidence 0.00 Published 2010 Journal PLoS ONE Section Body Doc Link PMC2854715 Disease Relevance 0 Pain Relevance 0
For example, the affinity of D-4F for arachidonic and linoleic acid, POVPC, PEIPC and KODia-PC appear to be considerably higher than that of OxP-11D.
D-4F Binding (affinity) of OxP-11D
3) Confidence 0.00 Published 2010 Journal PLoS ONE Section Body Doc Link PMC2854715 Disease Relevance 0.13 Pain Relevance 0.03
D-4F and OxP-11D bound these sterols similarly (Table 3).
D-4F Binding (bound) of OxP-11D
4) Confidence 0.00 Published 2010 Journal PLoS ONE Section Body Doc Link PMC2854715 Disease Relevance 0.15 Pain Relevance 0.03
In surface plasmon resonance binding studies, OxP-11D bound oxidized (phospho)lipids and sterols in much the same manner as D-4F, a widely studied cardioprotective apoA-I-mimetic peptide with anti-inflammatory properties.
D-4F Binding (bound) of OxP-11D associated with inflammation
5) Confidence 0.00 Published 2010 Journal PLoS ONE Section Abstract Doc Link PMC2854715 Disease Relevance 0.34 Pain Relevance 0.17
OxP-11D bound five of the lipids with higher affinity than D-4F, including palmitic acid, 5(S)-HPETE, 12(S)-HPETE, 15(S)-HPETE, 13(S) and 13(S)-HODE.
D-4F Binding (bound) of OxP-11D
6) Confidence 0.00 Published 2010 Journal PLoS ONE Section Body Doc Link PMC2854715 Disease Relevance 0.14 Pain Relevance 0.03

General Comments

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