INT305838

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Context Info
Confidence 0.53
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 4
Disease Relevance 1.10
Pain Relevance 0.87

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

extracellular space (Tslp) extracellular region (Tslp)
Anatomy Link Frequency
dendritic cells 2
Tslp (Mus musculus)
Pain Link Frequency Relevance Heat
Inflammation 24 99.62 Very High Very High Very High
cytokine 76 94.88 High High
chemokine 80 78.40 Quite High
Inflammatory mediators 4 54.84 Quite High
anesthesia 4 5.00 Very Low Very Low Very Low
halothane 4 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
INFLAMMATION 28 99.62 Very High Very High Very High
Eosinophilia 4 83.80 Quite High
Hypersensitivity 28 81.56 Quite High
Asthma 12 68.12 Quite High
Eczema 88 67.68 Quite High
Pressure And Volume Under Development 4 38.04 Quite Low
Injury 4 37.24 Quite Low
Rhinitis 12 30.88 Quite Low
Toxicity 24 5.00 Very Low Very Low Very Low
Disease 16 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
This result is consistent with the enhancement of TSLP expression.
Positive_regulation (enhancement) of Gene_expression (expression) of TSLP
1) Confidence 0.53 Published 2010 Journal Environ Health Perspect Section Body Doc Link PMC2854722 Disease Relevance 0.59 Pain Relevance 0.25
Therefore, DINP may activate dendritic cells in Dp-related inflammatory sites through the enhancement of TSLP production.
Positive_regulation (enhancement) of Gene_expression (production) of TSLP in dendritic cells associated with inflammation
2) Confidence 0.53 Published 2010 Journal Environ Health Perspect Section Body Doc Link PMC2854722 Disease Relevance 0.51 Pain Relevance 0.25
On the other hand, DINP at 0.15 mg/kg/day significantly increased TSLP expression compared with vehicle in the presence of intradermal Dp (p < 0.05).
Positive_regulation (increased) of Gene_expression (expression) of TSLP
3) Confidence 0.38 Published 2010 Journal Environ Health Perspect Section Body Doc Link PMC2854722 Disease Relevance 0 Pain Relevance 0.16
Dp injection alone increased the expression of eotaxin, eotaxin-2, and TSLP compared with saline injection (see Supplemental Material, Table 1; eotaxin, p < 0.01).
Positive_regulation (increased) of Gene_expression (expression) of TSLP
4) Confidence 0.33 Published 2010 Journal Environ Health Perspect Section Body Doc Link PMC2854722 Disease Relevance 0 Pain Relevance 0.20

General Comments

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