INT305875

Context Info Confidence 0.03 First Reported 2010 Last Reported 2010 Negated 0 Speculated 1 Reported most in Body Documents 1 Total Number 1 Disease Relevance 0.11 Pain Relevance 0.04

cytosol (Ocln) mitochondrion (Pcx) structural molecule activity (Ocln) plasma membrane (Ocln)

Pcx (Mus musculus) Ocln (Mus musculus)

Pain Link Frequency Relevance Heat agonist 1 89.56 Inflammatory mediators 1 48.84 Central nervous system 3 29.24 Neurobehavioral 1 12.64 imagery 2 5.00 metalloproteinase 1 5.00 anesthesia 1 5.00

Disease Link Frequency Relevance Heat Cancer 21 61.08 Breast Cancer 1 51.44 Metastasis 25 50.00 Adhesions 2 49.64 INFLAMMATION 1 48.44 Stress 3 46.48 Central Nervous System Disease 2 29.56 Brain Tumor 6 23.36 Dementia 1 22.64 Motor Neuron Diseases 1 21.36

Sentences Mentioned In

Key:

Protein

Mutation

Event

Anatomy

Negation

Speculation

Pain term

Disease term

Exposure to PCB118 and PCB153 modulated expressional levels of claudin-5 and ZO-1, whereas PCB126 appeared to primarily influence the coassociation of occludin and ZO-1.

PCB126 Negative_regulation (influence) of occludin Spec (appeared) Binding (coassociation) of

1) Confidence 0.03 Published 2010 Journal Environ Health Perspect Section Body Doc Link PMC2854723 Disease Relevance 0.11 Pain Relevance 0.04

General Comments

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