INT305881

Context Info Confidence 0.01 First Reported 2010 Last Reported 2010 Negated 0 Speculated 0 Reported most in Body Documents 1 Total Number 1 Disease Relevance 0 Pain Relevance 0

plasma membrane (Ocln, Tjp1) cytosol (Ocln) Golgi apparatus (Tjp1) structural molecule activity (Ocln) nucleus (Tjp1) cytoplasm (Tjp1)

Ocln (Mus musculus) Tjp1 (Mus musculus)

Pain Link Frequency Relevance Heat Central nervous system 3 5.00 imagery 2 5.00 Inflammatory mediators 1 5.00 Neurobehavioral 1 5.00 metalloproteinase 1 5.00 agonist 1 5.00 anesthesia 1 5.00

Disease Link Frequency Relevance Heat Metastasis 25 50.00 Melanoma 12 7.92 Cancer 21 5.00 Brain Tumor 6 5.00 Stress 3 5.00 Body Weight 2 5.00 Adhesions 2 5.00 Central Nervous System Disease 2 5.00 Parkinson's Disease 1 5.00 Poisoning 1 5.00

Sentences Mentioned In

Key:

Protein

Mutation

Event

Anatomy

Negation

Speculation

Pain term

Disease term

Confocal microscopy suggests that PCB treatment can enhance the association between ZO-1 and occludin, as shown in yellow in the merged and phase-contrast micrographs in Figure 3 (arrows).

Positive_regulation (enhance) of occludin Binding (association) of ZO-1

1) Confidence 0.01 Published 2010 Journal Environ Health Perspect Section Body Doc Link PMC2854723 Disease Relevance 0 Pain Relevance 0

General Comments

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