INT305882

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Context Info
Confidence 0.03
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.62
Pain Relevance 0

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

mitochondrion (Pcx) cytoskeleton (Alms1) cilium (Alms1)
molecular_function (Alms1) lipid metabolic process (Alms1) cytoplasm (Alms1)
Anatomy Link Frequency
brain 1
Pcx (Mus musculus)
Alms1 (Mus musculus)
Pain Link Frequency Relevance Heat
metalloproteinase 1 19.16 Low Low
Central nervous system 3 5.00 Very Low Very Low Very Low
imagery 2 5.00 Very Low Very Low Very Low
Inflammatory mediators 1 5.00 Very Low Very Low Very Low
Neurobehavioral 1 5.00 Very Low Very Low Very Low
agonist 1 5.00 Very Low Very Low Very Low
anesthesia 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Metastasis 25 99.40 Very High Very High Very High
Cancer 21 84.36 Quite High
Melanoma 12 70.72 Quite High
Brain Tumor 6 30.56 Quite Low
Stress 3 5.00 Very Low Very Low Very Low
Body Weight 2 5.00 Very Low Very Low Very Low
Adhesions 2 5.00 Very Low Very Low Very Low
Central Nervous System Disease 2 5.00 Very Low Very Low Very Low
Parkinson's Disease 1 5.00 Very Low Very Low Very Low
Poisoning 1 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
These results suggest that alteration of BBB integrity is the underlying mechanism of PCB-induced brain metastases and may also be involved in neurotoxic and neurodevelopmental effects of these environmental toxicants.



PCB Binding (integrity) of BBB in brain associated with metastasis
1) Confidence 0.03 Published 2010 Journal Environ Health Perspect Section Body Doc Link PMC2854723 Disease Relevance 0.62 Pain Relevance 0

General Comments

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