INT305978

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Context Info
Confidence 0.86
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.88
Pain Relevance 0.17

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

endoplasmic reticulum (SELS) plasma membrane (SELS) enzyme binding (SELS)
cytoplasm (SELS)
Anatomy Link Frequency
reticulum 1
SELS (Homo sapiens)
Pain Link Frequency Relevance Heat
Inflammation 11 89.44 High High
cytokine 8 88.40 High High
adenocard 2 5.00 Very Low Very Low Very Low
COX2 1 5.00 Very Low Very Low Very Low
member 8 1 5.00 Very Low Very Low Very Low
Inflammatory response 1 5.00 Very Low Very Low Very Low
Neurotransmitter 1 5.00 Very Low Very Low Very Low
Neuropeptide 1 5.00 Very Low Very Low Very Low
chemokine 1 5.00 Very Low Very Low Very Low
Kinase C 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Stress 14 93.52 High High
INFLAMMATION 12 89.44 High High
Apoptosis 12 83.28 Quite High
Chronic Disease 1 79.84 Quite High
Obesity 1 77.84 Quite High
Diabetes Mellitus 4 77.12 Quite High
Cardiovascular Disease 1 75.44 Quite High
Aging 5 5.00 Very Low Very Low Very Low
Cancer 4 5.00 Very Low Very Low Very Low
Insulin Resistance 3 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Selenoprotein S (SelS) is a glucose-regulated Sec-containing protein expressed in the endoplasmic reticulum (ER) membrane that participates in retrotranslocation of misfolded proteins from the ER to the cytosol, where they are ubiquitinated and degraded at the proteasome [84].
Protein_catabolism (degraded) of SelS in reticulum
1) Confidence 0.86 Published 2010 Journal Biol Trace Elem Res Section Body Doc Link PMC2855032 Disease Relevance 0.88 Pain Relevance 0.17

General Comments

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