INT3060
From wiki-pain
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Sentences Mentioned In
Key: | Protein | Mutation | Event | Anatomy | Negation | Speculation | Pain term | Disease term |
Enhanced mortality from succinylcholine is generally observed when serum butyrylcholinesterase is inhibited 55-94%. | |||||||||||||||
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The antinociceptive activity of donepezil, a novel cholinesterase inhibitor, was investigated in the mouse hot plate test. | |||||||||||||||
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Physostigmine, a central and peripheral cholinesterase inhibitor produced tremors, and at high doses death, by respiratory paralysis. | |||||||||||||||
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Neostigmine, a selective peripheral cholinesterase inhibitor, induced respiratory paralysis which was not affected by clonidine pretreatment. | |||||||||||||||
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In general anesthesia with thiopentone and halothane, the pseudocholinesterase activity diminished. | |||||||||||||||
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Pseudocholinesterase deficiency: an additional preoperative consideration in outpatient diagnostic procedures. | |||||||||||||||
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At therapeutic concentrations needed to treat cardiac arrhythmias (2 to 5 micrograms/ml), quinidine inhibited pseudocholinesterase activity by 60% to 70%. | |||||||||||||||
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These results were corroborated with two other specific inhibitors of AChE and BChE, tolserine and bis-norcymserine, respectively. | |||||||||||||||
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Physostigmine decreased atrial cholinesterase activity by 80% and increased the fraction of stimulation-evoked unhydrolyzed 14C-acetylcholine in the persufates from 58 to 86%. | |||||||||||||||
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The authors previously reported a case of decreased pseudocholinesterase activity in a patient with HELLP syndrome. | |||||||||||||||
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The prevalence of reduced pseudocholinesterase activity lower than normal limit was 60.0% (9/15) in patients with HELLP syndrome, 33.3% (5/15) in patients with severe preeclampsia, and 6.6% (1/15) in women with normal pregnancy, respectively (P =.009). | |||||||||||||||
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It was assumed that the reduced pseudocholinesterase activity in HELLP syndrome is associated with impaired liver function. | |||||||||||||||
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Considering the increased prevalence of reduced pseudocholinesterase activity in patients with HELLP syndrome, the authors suggest that whenever general anesthesia is applied in these patients, the anesthesiologist should be aware that the patient may show slow metabolic degradation of choline-ester drugs. | |||||||||||||||
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The influence of clonidine on the toxicity produced by two irreversible, organophosphate cholinesterase inhibitors, soman and echothiophate, was studied in mice. | |||||||||||||||
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Plasma cholinesterase activity was significantly reduced with the use of neostigmine but not with edrophonium (P < 0.001). | |||||||||||||||
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We report a case of decreased plasma pseudocholinesterase activity in a patient with hemolysis, elevated liver enzymes, and low platelets (HELLP) syndrome. | |||||||||||||||
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The findings suggest that prolactin may exert its cholinomimetic activity by inhibition of cholinesterase. | |||||||||||||||
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Complaints (headache, dizziness, fatigue, nausea, breathing problems, abdominal cramps, and tingling in extremities) were associated with within-normal depressions in cholinesterase activity. | |||||||||||||||
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Plasma cholinesterase activity was decreased to 29% of control at 15 min and remained at approximately 60% of the control after neostigmine administration. | |||||||||||||||
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Organophosphorus pesticide-induced butyrylcholinesterase inhibition and potentiation of succinylcholine toxicity in mice. | |||||||||||||||
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