INT306006

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Context Info
Confidence 0.06
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.63
Pain Relevance 0.04

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

extracellular space (CD14, LBP) extracellular region (CD14, LBP) lipid binding (LBP)
transport (LBP) plasma membrane (CD14)
CD14 (Homo sapiens)
LBP (Homo sapiens)
Pain Link Frequency Relevance Heat
cytokine 22 87.20 High High
ketamine 12 5.00 Very Low Very Low Very Low
Inflammation 12 5.00 Very Low Very Low Very Low
Morphine 6 5.00 Very Low Very Low Very Low
Inflammatory response 6 5.00 Very Low Very Low Very Low
Central nervous system 5 5.00 Very Low Very Low Very Low
Nicotine 4 5.00 Very Low Very Low Very Low
Opioid 4 5.00 Very Low Very Low Very Low
antagonist 3 5.00 Very Low Very Low Very Low
agonist 3 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Sepsis 39 93.00 High High
Death 4 80.52 Quite High
Fungal Infection 1 72.08 Quite High
INFLAMMATION 19 5.00 Very Low Very Low Very Low
Infection 5 5.00 Very Low Very Low Very Low
Pain 3 5.00 Very Low Very Low Very Low
Disease 3 5.00 Very Low Very Low Very Low
Endotoxemia 3 5.00 Very Low Very Low Very Low
Critical Illness 2 5.00 Very Low Very Low Very Low
Cardiovascular Disease 2 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
About 12 years ago, the discovery of the Toll-like receptor (TLR) unravelled the missing link between endotoxin recognition by LBP and CD14 and the intracellular signalling pathway, leading to the activation and translocation of NF?
CD14 Binding (recognition) of LBP
1) Confidence 0.06 Published 2010 Journal Mediators of Inflammation Section Body Doc Link PMC2855078 Disease Relevance 0.63 Pain Relevance 0.04

General Comments

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