INT306020

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Context Info
Confidence 0.13
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.34
Pain Relevance 0.66

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

transport (LBP) intracellular (Tlr4) cytoplasm (Tlr4)
lipid binding (LBP) extracellular space (LBP) signal transduction (Tlr4)
LBP (Homo sapiens)
Tlr4 (Mus musculus)
Pain Link Frequency Relevance Heat
ketamine 12 99.68 Very High Very High Very High
cytokine 22 86.76 High High
Inflammation 12 86.36 High High
agonist 3 84.56 Quite High
Nicotine 4 54.56 Quite High
tolerance 2 46.44 Quite Low
ischemia 2 38.48 Quite Low
Inflammatory response 6 30.64 Quite Low
Morphine 6 5.00 Very Low Very Low Very Low
Central nervous system 5 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
INFLAMMATION 19 86.36 High High
Sepsis 39 58.64 Quite High
Sleep Disorders 1 57.40 Quite High
Pancreatitis 1 39.92 Quite Low
Cv Unclassified Under Development 1 38.48 Quite Low
Syndrome 2 36.80 Quite Low
Paralysis 1 27.80 Quite Low
Apoptosis 1 24.36 Low Low
Infection 5 5.00 Very Low Very Low Very Low
Death 4 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Not only does ketamine interfere with LPS binding to LBP, but it also decreases phosphorylation of various kinases involved in the TLR4 intracellular signalling [60].
LBP Binding (binding) of LPS associated with ketamine
1) Confidence 0.13 Published 2010 Journal Mediators of Inflammation Section Body Doc Link PMC2855078 Disease Relevance 0.34 Pain Relevance 0.66

General Comments

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