INT306108

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Context Info
Confidence 0.03
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.15
Pain Relevance 0.20

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytoplasm (CCL2, Mapk3) signal transduction (CCL2, Mapk3) nucleoplasm (Mapk3)
aging (CCL2) protein complex assembly (Mapk3) protein complex (Mapk3)
Anatomy Link Frequency
THP-1 2
CCL2 (Homo sapiens)
Mapk3 (Mus musculus)
Pain Link Frequency Relevance Heat
chemokine 13 93.04 High High
agonist 15 86.08 High High
analgesia 1 5.00 Very Low Very Low Very Low
noradrenaline 1 5.00 Very Low Very Low Very Low
Catecholamine 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Bordatella Infection 7 86.56 High High
Adhesions 2 5.00 Very Low Very Low Very Low
Injury 1 5.00 Very Low Very Low Very Low
Sleep Disorders 1 5.00 Very Low Very Low Very Low
Acquired Immune Deficiency Syndrome Or Hiv Infection 1 5.00 Very Low Very Low Very Low
Stress 1 5.00 Very Low Very Low Very Low
Vesicular Stomatitis 1 5.00 Very Low Very Low Very Low
Pressure Volume 2 Under Development 1 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
We used Western blot analysis to detect dual phosphorylated ERK1/2 (dpERK) and show that in THP-1 cells CCL2 induced a marked activation of ERK1/2 (Figure 3B, lane 2).
CCL2 Positive_regulation (induced) of Positive_regulation (activation) of ERK1 in THP-1
1) Confidence 0.03 Published 2010 Journal PLoS ONE Section Body Doc Link PMC2855346 Disease Relevance 0.15 Pain Relevance 0.20

General Comments

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