INT306135

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Context Info
Confidence 0.22
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Abstract
Documents 1
Total Number 4
Disease Relevance 2.13
Pain Relevance 0

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytosol (Omp) signal transduction (Omp) nucleus (Omp)
cytoplasm (Omp) signal transducer activity (Omp)
Anatomy Link Frequency
VRNs 1
ORNs 1
Omp (Mus musculus)
Pain Link Frequency Relevance Heat
medulla 24 5.00 Very Low Very Low Very Low
ketamine 4 5.00 Very Low Very Low Very Low
anesthesia 4 5.00 Very Low Very Low Very Low
Peripheral nervous system 4 5.00 Very Low Very Low Very Low
Inflammation 4 5.00 Very Low Very Low Very Low
imagery 4 5.00 Very Low Very Low Very Low
Hyperesthesia 4 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Encephalopathy 300 95.92 Very High Very High Very High
Disease 36 90.20 High High
Infection 268 80.64 Quite High
Sprains And Strains 12 77.16 Quite High
Scrapie 92 25.00 Low Low
Creutzfeldt Jakob Disease 56 25.00 Low Low
Chronic Wasting Disease 12 25.00 Low Low
Lifespan 8 25.00 Low Low
Neurodegenerative Disease 4 25.00 Low Low
Exsanguination 4 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
The Manders Overlap Coefficient, M2, was calculated in order to determine the percentage of PrPSc immunofluorescence that co-localized with the OMP signal in a selected region.
Localization (localized) of OMP
1) Confidence 0.22 Published 2010 Journal PLoS Pathogens Section Body Doc Link PMC2855443 Disease Relevance 0.22 Pain Relevance 0
For each portion of the ORN there was greater than a 90% co-localization of the PrPSc signal with OMP (M2>0.90, Table 1).
Localization (localization) of OMP
2) Confidence 0.22 Published 2010 Journal PLoS Pathogens Section Body Doc Link PMC2855443 Disease Relevance 0.33 Pain Relevance 0
PrPSc co-localized with olfactory marker protein in the soma and dendrites of ORNs and VRNs and also with adenylyl cyclase III, which is present in the sensory cilia of ORNs that project into the lumen of the nasal airway.
Localization (localized) of marker protein in ORNs
3) Confidence 0.22 Published 2010 Journal PLoS Pathogens Section Abstract Doc Link PMC2855443 Disease Relevance 0.79 Pain Relevance 0
PrPSc co-localized with olfactory marker protein in the soma and dendrites of ORNs and VRNs and also with adenylyl cyclase III, which is present in the sensory cilia of ORNs that project into the lumen of the nasal airway.
Localization (localized) of marker protein in VRNs
4) Confidence 0.07 Published 2010 Journal PLoS Pathogens Section Abstract Doc Link PMC2855443 Disease Relevance 0.79 Pain Relevance 0

General Comments

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