INT306170

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Context Info
Confidence 0.07
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 13
Disease Relevance 9.66
Pain Relevance 0.03

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

nucleoplasm (PRPF19) lipid particle (PRPF19) cytoskeleton (PRPF19)
nucleus (PRPF19) DNA binding (PRPF19) cytoplasm (PRPF19)
Anatomy Link Frequency
urine 6
bladder 4
muscle 2
WBC 1
PRPF19 (Homo sapiens)
Pain Link Frequency Relevance Heat
Inflammation 13 63.80 Quite High
Pain 13 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Cancer 221 99.88 Very High Very High Very High
Hematuria 195 99.76 Very High Very High Very High
Disease 52 99.74 Very High Very High Very High
Bladder Cancer 702 98.52 Very High Very High Very High
Pyuria 91 95.88 Very High Very High Very High
Infection 13 65.08 Quite High
INFLAMMATION 13 63.80 Quite High
Acquired Immune Deficiency Syndrome Or Hiv Infection 13 61.68 Quite High
Recurrence 39 29.84 Quite Low
Urolithiasis 13 20.04 Low Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
The specificity of the NMP22BC test was 59.2% in the hematuria group with >5 WBC/HPF and 89.6% in the hematuria group with ?
Regulation (specificity) of NMP22BC in WBC associated with hematuria
1) Confidence 0.07 Published 2010 Journal Korean Journal of Urology Section Body Doc Link PMC2855476 Disease Relevance 0.93 Pain Relevance 0
The greater sensitivity of the NMP22BC test may be useful for the diagnosis of non-muscle-invasive and low-grade bladder cancer but not for the diagnosis of invasive and high-grade bladder cancers.
Regulation (sensitivity) of NMP22BC in bladder associated with bladder cancer
2) Confidence 0.04 Published 2010 Journal Korean Journal of Urology Section Body Doc Link PMC2855476 Disease Relevance 0.94 Pain Relevance 0.03
The sensitivity of the NMP22BC test (81.8%) in non-muscle-invasive bladder cancer was higher than that of cytology (36.4%).
Regulation (sensitivity) of NMP22BC in bladder associated with bladder cancer
3) Confidence 0.04 Published 2010 Journal Korean Journal of Urology Section Abstract Doc Link PMC2855476 Disease Relevance 0.73 Pain Relevance 0
However, for the 14 patients with invasive cancer, the sensitivity of urine cytology was 92.9%, which was higher than the 57.1% sensitivity of the NMP22BC test, but this difference was not statistically significant (p>0.05) (Table 4).
Regulation (sensitivity) of NMP22BC in urine associated with cancer
4) Confidence 0.04 Published 2010 Journal Korean Journal of Urology Section Body Doc Link PMC2855476 Disease Relevance 0.81 Pain Relevance 0
In our study, the sensitivity of the NMP22BC test was 81.8% for non-muscle-invasive bladder cancer, which was higher than the sensitivity of 36.4% for urine cytology (p<0.01).
Regulation (sensitivity) of NMP22BC in muscle associated with bladder cancer
5) Confidence 0.04 Published 2010 Journal Korean Journal of Urology Section Body Doc Link PMC2855476 Disease Relevance 0.77 Pain Relevance 0
The sensitivity of the NMP22BC test (77.5%) was significantly higher than that of urine cytology (46.3%).
Regulation (sensitivity) of NMP22BC in urine
6) Confidence 0.04 Published 2010 Journal Korean Journal of Urology Section Abstract Doc Link PMC2855476 Disease Relevance 0.63 Pain Relevance 0
In our study, the sensitivity of the NMP22BC test performed on 1,070 patients who visited our hospital for hematuria or for follow-up observation of bladder cancer was 77.5%, and the specificity was 88.8%.
Regulation (sensitivity) of NMP22BC in bladder associated with bladder cancer and hematuria
7) Confidence 0.04 Published 2010 Journal Korean Journal of Urology Section Body Doc Link PMC2855476 Disease Relevance 0.56 Pain Relevance 0
When sensitivity was calculated according to tumor grade, the NMP22BC test had a sensitivity of 83.9% and urine cytology had a sensitivity of 37.5% for low-grade cancer (p<0.01); for high-grade tumors, the sensitivity of the NMP22BC test was 62.5% and that for urine cytology was 66.7% (the difference was not statistically significant; p>0.05) (Table 5).
Regulation (sensitivity) of NMP22BC in urine associated with cancer
8) Confidence 0.04 Published 2010 Journal Korean Journal of Urology Section Body Doc Link PMC2855476 Disease Relevance 0.86 Pain Relevance 0
For invasive cancer, the sensitivity of the NMP22BC test was 57.1%, which was lower than the 92.9% sensitivity of urine cytology; however, this difference was not statistically significant (p>0.05).
Regulation (sensitivity) of NMP22BC in urine associated with cancer
9) Confidence 0.04 Published 2010 Journal Korean Journal of Urology Section Body Doc Link PMC2855476 Disease Relevance 0.93 Pain Relevance 0
However, the sensitivity of the NMP22BC test and of urine cytology in invasive bladder cancer were 57.1% and 92.9%, respectively.
Regulation (sensitivity) of NMP22BC in bladder associated with bladder cancer
10) Confidence 0.04 Published 2010 Journal Korean Journal of Urology Section Abstract Doc Link PMC2855476 Disease Relevance 0.80 Pain Relevance 0
The sensitivity of the NMP22BC test was 77.5%, which was higher than the sensitivity of urine cytology, which was 46.3%.
Regulation (sensitivity) of NMP22BC in urine
11) Confidence 0.04 Published 2010 Journal Korean Journal of Urology Section Body Doc Link PMC2855476 Disease Relevance 0.20 Pain Relevance 0
The greater sensitivity of the NMP22BC test may be more useful for the diagnosis of non-muscle-invasive bladder cancer and low-grade bladder cancer than for the diagnosis of invasive or high-grade bladder cancer.
Regulation (sensitivity) of NMP22BC in muscle associated with bladder cancer
12) Confidence 0.04 Published 2010 Journal Korean Journal of Urology Section Abstract Doc Link PMC2855476 Disease Relevance 0.87 Pain Relevance 0
For all disease stages, the sensitivity of the NMP22BC test was higher than the sensitivity of urine cytology; as the degree of cell differentiation increased, the sensitivity became higher [12].
Regulation (sensitivity) of NMP22BC in urine associated with disease
13) Confidence 0.04 Published 2010 Journal Korean Journal of Urology Section Body Doc Link PMC2855476 Disease Relevance 0.62 Pain Relevance 0

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