INT306241

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Context Info
Confidence 0.00
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.91
Pain Relevance 0.08

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

carbohydrate metabolic process (Ins1, PCK1) cytoplasm (Ins1, PCK1) small molecule metabolic process (PCK1)
lyase activity (PCK1) lipid metabolic process (PCK1) cytosol (PCK1)
Ins1 (Rattus norvegicus)
PCK1 (Homo sapiens)
Pain Link Frequency Relevance Heat
cytokine 3 84.24 Quite High
tolerance 5 80.52 Quite High
Inflammation 2 5.00 Very Low Very Low Very Low
alcohol 2 5.00 Very Low Very Low Very Low
Bioavailability 2 5.00 Very Low Very Low Very Low
fibrosis 1 5.00 Very Low Very Low Very Low
Pain 1 5.00 Very Low Very Low Very Low
Potency 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Hepatocellular Cancer 3 98.00 Very High Very High Very High
Diabetes Mellitus 21 92.64 High High
Chronic Disease 2 55.52 Quite High
Metabolic Syndrome 10 53.00 Quite High
Dyslipidemia /

Combined Dyslipidemia

1 52.08 Quite High
Hypertension 1 51.52 Quite High
Cardiovascular Disease 2 50.20 Quite High
Injury 2 16.92 Low Low
Thrombosis 1 10.48 Low Low
Cancer 7 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
The investigators showed that EGCG mimics insulin, increases tyrosine phosphorylation of the insulin receptor and the insulin receptor substrate, and reduces gene expression of the gluconeogenic enzyme phosphoenolpyruvate carboxykinase.
insulin Negative_regulation (reduces) of Gene_expression (expression) of carboxykinase
1) Confidence 0.00 Published 2010 Journal Chin Med Section Body Doc Link PMC2855614 Disease Relevance 0.85 Pain Relevance 0.08

General Comments

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