INT306255

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Context Info
Confidence 0.01
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0
Pain Relevance 0.07

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

nucleus (IRF6, TFAM) DNA binding (IRF6, TFAM) cytosol (IRF6)
mitochondrion (TFAM) cytoplasm (IRF6)
IRF6 (Homo sapiens)
TFAM (Homo sapiens)
Pain Link Frequency Relevance Heat
cytokine 17 89.08 High High
Arthritis 106 18.96 Low Low
Etanercept 3 6.56 Low Low
Infliximab 1 5.60 Low Low
Inflammation 19 5.00 Very Low Very Low Very Low
dexamethasone 7 5.00 Very Low Very Low Very Low
methotrexate 6 5.00 Very Low Very Low Very Low
metalloproteinase 4 5.00 Very Low Very Low Very Low
Inflammatory response 3 5.00 Very Low Very Low Very Low
Pain 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Cancer 11 49.92 Quite Low
Necrosis 2 49.44 Quite Low
Apoptosis 12 25.36 Quite Low
Rheumatoid Arthritis 103 18.96 Low Low
Insulin Resistance 2 18.40 Low Low
INFLAMMATION 22 5.00 Very Low Very Low Very Low
Disease 12 5.00 Very Low Very Low Very Low
Leukemia 5 5.00 Very Low Very Low Very Low
Arthritis 5 5.00 Very Low Very Low Very Low
Stress 5 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
It has been shown that in cells expressing the 299D-399T TLR4, LPS activated the transcription factor NFB and increased the expression of IL6 and TNF-.
LPS Positive_regulation (activated) of transcription factor
1) Confidence 0.01 Published 2010 Journal PLoS ONE Section Body Doc Link PMC2855702 Disease Relevance 0 Pain Relevance 0.07

General Comments

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