INT306256

From wiki-pain
Jump to: navigation, search
Context Info
Confidence 0.23
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.44
Pain Relevance 0

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

nucleoplasm (MDM2, TP53) nucleus (MDM2, TP53) protein complex assembly (MDM2, TP53)
enzyme binding (MDM2, TP53) protein complex (MDM2, TP53) cytoplasm (MDM2, TP53)
Anatomy Link Frequency
nucleus 2
MDM2 (Homo sapiens)
TP53 (Homo sapiens)
Pain Link Frequency Relevance Heat
Arthritis 106 46.40 Quite Low
Inflammation 19 38.28 Quite Low
cytokine 17 26.12 Quite Low
dexamethasone 7 5.00 Very Low Very Low Very Low
methotrexate 6 5.00 Very Low Very Low Very Low
metalloproteinase 4 5.00 Very Low Very Low Very Low
Inflammatory response 3 5.00 Very Low Very Low Very Low
Etanercept 3 5.00 Very Low Very Low Very Low
Pain 2 5.00 Very Low Very Low Very Low
Osteoarthritis 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Apoptosis 12 93.24 High High
Leukemia 5 90.84 High High
Pancreatic Cancer 1 88.20 High High
Rheumatoid Arthritis 103 46.40 Quite Low
Disease 12 38.64 Quite Low
INFLAMMATION 22 38.28 Quite Low
Cancer 11 5.00 Very Low Very Low Very Low
Arthritis 5 5.00 Very Low Very Low Very Low
Stress 5 5.00 Very Low Very Low Very Low
Autoimmune Disease 5 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
It is connected to three genes: TP53 in its active state in the nucleus (through state_transition), TPPP (TPPP can phosphorylate TP53) and MDM2 (MDM2 can inhibit the activation of TP53).
MDM2 Negative_regulation (inhibit) of Positive_regulation (activation) of TP53 in nucleus
1) Confidence 0.23 Published 2010 Journal PLoS ONE Section Body Doc Link PMC2855702 Disease Relevance 0.44 Pain Relevance 0

General Comments

This test has worked.

Personal tools
Namespaces

Variants
Actions
Navigation
Toolbox