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Context Info
Confidence 0.09
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.89
Pain Relevance 0.78

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

intracellular (TNF) extracellular matrix organization (TNF) cytoplasm (HDAC4)
cytosol (HDAC4) signal transduction (TNF) extracellular space (TNF)
HDAC4 (Homo sapiens)
TNF (Homo sapiens)
Pain Link Frequency Relevance Heat
dexamethasone 7 96.36 Very High Very High Very High
Adalimumab 1 93.92 High High
Infliximab 1 93.32 High High
methotrexate 6 92.96 High High
Etanercept 3 92.84 High High
Arthritis 106 92.36 High High
cytokine 17 86.96 High High
Inflammatory response 3 70.80 Quite High
Inflammation 19 27.44 Quite Low
metalloproteinase 4 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Rheumatoid Arthritis 103 92.36 High High
Cancer 11 87.72 High High
Insulin Resistance 2 87.24 High High
Apoptosis 12 83.40 Quite High
Necrosis 2 71.32 Quite High
INFLAMMATION 22 70.80 Quite High
Disease 12 5.00 Very Low Very Low Very Low
Leukemia 5 5.00 Very Low Very Low Very Low
Arthritis 5 5.00 Very Low Very Low Very Low
Stress 5 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
The expression of TNF was inhibited by histone deacetylase (HDAC) in affected synovial tissue [94].
histone deacetylase Negative_regulation (inhibited) of Gene_expression (expression) of TNF
1) Confidence 0.09 Published 2010 Journal PLoS ONE Section Body Doc Link PMC2855702 Disease Relevance 0.89 Pain Relevance 0.78

General Comments

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