INT306264

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Context Info
Confidence 0.09
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.74
Pain Relevance 0.61

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cell proliferation (IL1A) cytosol (IL1A) mitochondrion (MTX1)
extracellular space (IL1A) extracellular region (IL1A)
IL1A (Homo sapiens)
MTX1 (Homo sapiens)
Pain Link Frequency Relevance Heat
Arthritis 106 100.00 Very High Very High Very High
methotrexate 6 92.08 High High
Inflammation 19 87.84 High High
cytokine 17 84.28 Quite High
dexamethasone 7 75.88 Quite High
Inflammatory response 3 66.52 Quite High
Adalimumab 1 42.84 Quite Low
Infliximab 1 42.24 Quite Low
Etanercept 3 41.76 Quite Low
metalloproteinase 4 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Rheumatoid Arthritis 103 100.00 Very High Very High Very High
Disease 12 95.68 Very High Very High Very High
INFLAMMATION 22 87.84 High High
Apoptosis 12 71.12 Quite High
Cancer 11 36.64 Quite Low
Insulin Resistance 2 36.16 Quite Low
Necrosis 2 20.24 Low Low
Leukemia 5 5.00 Very Low Very Low Very Low
Arthritis 5 5.00 Very Low Very Low Very Low
Stress 5 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
It has been shown that the effect of MTX treated on RA is associated with the genotype of IL1 gene.
IL1 Binding (associated) of MTX associated with arthritis
1) Confidence 0.09 Published 2010 Journal PLoS ONE Section Body Doc Link PMC2855702 Disease Relevance 0.74 Pain Relevance 0.61

General Comments

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