INT306270

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Context Info
Confidence 0.34
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.31
Pain Relevance 0.12

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

small molecule metabolic process (PTGS2) endoplasmic reticulum (PTGS2) enzyme binding (PTGS2)
protein complex (PTGS2) cytoplasm (PTGS2) cell-cell signaling (CCL4)
CCL4 (Homo sapiens)
PTGS2 (Homo sapiens)
Pain Link Frequency Relevance Heat
Arthritis 106 90.76 High High
Inflammation 19 82.64 Quite High
cytokine 17 70.48 Quite High
dexamethasone 7 5.00 Very Low Very Low Very Low
methotrexate 6 5.00 Very Low Very Low Very Low
metalloproteinase 4 5.00 Very Low Very Low Very Low
Inflammatory response 3 5.00 Very Low Very Low Very Low
Etanercept 3 5.00 Very Low Very Low Very Low
Pain 2 5.00 Very Low Very Low Very Low
Osteoarthritis 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Rheumatoid Arthritis 103 90.76 High High
Disease 12 83.00 Quite High
INFLAMMATION 22 82.64 Quite High
Apoptosis 12 54.64 Quite High
Leukemia 5 42.88 Quite Low
Pancreatic Cancer 1 40.80 Quite Low
Reprotox - General 1 2 6.84 Low Low
Cancer 11 5.00 Very Low Very Low Very Low
Arthritis 5 5.00 Very Low Very Low Very Low
Stress 5 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
In Module 1, NFKB1 and CCL4 work together to activate the transcription of PTGS2 in the global interaction map, which forms part of the same cycle as JUN, mentioned above.
CCL4 Positive_regulation (activate) of Transcription (transcription) of PTGS2
1) Confidence 0.34 Published 2010 Journal PLoS ONE Section Body Doc Link PMC2855702 Disease Relevance 0.31 Pain Relevance 0.12

General Comments

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