INT306271

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Context Info
Confidence 0.30
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.85
Pain Relevance 0.80

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

extracellular space (IL1A, IL6) extracellular region (IL1A, IL6) cell proliferation (IL1A)
cytosol (IL1A) aging (IL6)
Anatomy Link Frequency
connective tissue 2
IL1A (Homo sapiens)
IL6 (Homo sapiens)
Pain Link Frequency Relevance Heat
dexamethasone 7 99.12 Very High Very High Very High
Arthritis 106 97.28 Very High Very High Very High
cytokine 17 90.48 High High
Inflammatory response 3 88.88 High High
Inflammation 19 83.60 Quite High
methotrexate 6 77.44 Quite High
Adalimumab 1 65.20 Quite High
Infliximab 1 64.60 Quite High
Etanercept 3 64.12 Quite High
metalloproteinase 4 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Rheumatoid Arthritis 103 97.28 Very High Very High Very High
Apoptosis 12 93.48 High High
INFLAMMATION 22 88.52 High High
Cancer 11 59.00 Quite High
Insulin Resistance 2 58.52 Quite High
Disease 12 49.52 Quite Low
Necrosis 2 42.60 Quite Low
Leukemia 5 5.00 Very Low Very Low Very Low
Arthritis 5 5.00 Very Low Very Low Very Low
Stress 5 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
DEX was also found to be a potent inhibitor of IL1-induced expression of the IL6 gene in connective tissue-type cells from the synovium of patients with RA.
IL1 Positive_regulation (induced) of Gene_expression (expression) of IL6 gene in connective tissue associated with dexamethasone and arthritis
1) Confidence 0.30 Published 2010 Journal PLoS ONE Section Body Doc Link PMC2855702 Disease Relevance 0.85 Pain Relevance 0.80

General Comments

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