INT306284

Context Info Confidence 0.28 First Reported 2010 Last Reported 2010 Negated 0 Speculated 0 Reported most in Body Documents 1 Total Number 1 Disease Relevance 0.13 Pain Relevance 0.09

nucleoplasm (CCNB1) protein complex assembly (CCNB1) cytoplasm (CCNB1) cytosol (CCNB1) nucleus (CCNB1) cytoskeleton (CCNB1)

CCNB1 (Homo sapiens)

Pain Link Frequency Relevance Heat Arthritis 106 79.24 methotrexate 6 51.92 Inflammation 19 29.48 cytokine 17 25.92 dexamethasone 7 17.52 Inflammatory response 3 8.16 metalloproteinase 4 5.00 Etanercept 3 5.00 Pain 2 5.00 Osteoarthritis 2 5.00

Disease Link Frequency Relevance Heat Rheumatoid Arthritis 103 79.24 Disease 12 46.32 INFLAMMATION 22 29.48 Arthritis 5 22.16 Cancer 11 16.80 Apoptosis 12 12.76 Leukemia 5 5.00 Stress 5 5.00 Autoimmune Disease 5 5.00 Death 3 5.00

Sentences Mentioned In

Key:

Protein

Mutation

Event

Anatomy

Negation

Speculation

Pain term

Disease term

The interaction between CCNB1 and CDC2 links the Blood_PBMC map and Synovial Fibrobalst map together.

CCNB1 Binding (interaction) of

1) Confidence 0.28 Published 2010 Journal PLoS ONE Section Body Doc Link PMC2855702 Disease Relevance 0.13 Pain Relevance 0.09

General Comments

This test has worked.