INT30629

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Context Info
Confidence 0.37
First Reported 1986
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 2
Total Number 2
Disease Relevance 1.35
Pain Relevance 0.59

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

extracellular space (SST) extracellular region (SST) cell-cell signaling (SST)
Anatomy Link Frequency
plasma 2
SST (Homo sapiens)
Pain Link Frequency Relevance Heat
Somatostatin 111 100.00 Very High Very High Very High
Opioid 1 96.56 Very High Very High Very High
imagery 6 59.28 Quite High
palliative 1 38.84 Quite Low
Serotonin 2 34.32 Quite Low
Dopamine 5 5.00 Very Low Very Low Very Low
agonist 3 5.00 Very Low Very Low Very Low
Potency 3 5.00 Very Low Very Low Very Low
dopamine receptor 1 5.00 Very Low Very Low Very Low
metalloproteinase 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Somatostatinoma 4 98.74 Very High Very High Very High
Achlorhydria 1 91.76 High High
Diarrhoea 10 90.40 High High
Gallstones 1 89.96 High High
Necrolytic Migratory Erythema 1 85.04 High High
Exanthema 2 83.80 Quite High
Glucagonoma 6 78.88 Quite High
Insulinoma 12 76.48 Quite High
Cancer 87 72.32 Quite High
Hypoglycemia 5 63.36 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
We have studied the effect of the intravenous administration of somatostatin (SRIF) on the thyrotropin (TSH) response to intravenous dermorphin (D), a new potent opioid peptide, in 7 healthy men.
Regulation (effect) of Positive_regulation (administration) of somatostatin associated with somatostatin and opioid
1) Confidence 0.37 Published 1986 Journal Horm. Res. Section Abstract Doc Link 2870974 Disease Relevance 0 Pain Relevance 0.31
Although it seems a paradox to treat patients with symptoms related to elevated SST levels with a somatostatinoma, in 1998 Angeletti et al showed that octreotide treatment was effective in reducing plasma levels of somatostatin and improving the related symptoms in three patients with metastatic somatostatinomas [48].
Regulation (effective) of Positive_regulation (reducing) of somatostatin in plasma associated with somatostatin and somatostatinoma
2) Confidence 0.37 Published 2010 Journal J Exp Clin Cancer Res Section Body Doc Link PMC2845555 Disease Relevance 1.35 Pain Relevance 0.28

General Comments

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