INT306297

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Context Info
Confidence 0.13
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.79
Pain Relevance 0.36

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

nucleolus (NFIB) nucleus (NFIB) intracellular (NFIB)
DNA binding (NFIB)
NFIB (Homo sapiens)
Pain Link Frequency Relevance Heat
Inflammation 19 97.24 Very High Very High Very High
cytokine 17 96.72 Very High Very High Very High
Osteoarthritis 2 84.88 Quite High
Arthritis 106 83.80 Quite High
dexamethasone 7 5.00 Very Low Very Low Very Low
methotrexate 6 5.00 Very Low Very Low Very Low
metalloproteinase 4 5.00 Very Low Very Low Very Low
Inflammatory response 3 5.00 Very Low Very Low Very Low
Etanercept 3 5.00 Very Low Very Low Very Low
Pain 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
INFLAMMATION 22 97.24 Very High Very High Very High
Autoimmune Disease 5 88.44 High High
Osteoarthritis 2 84.88 Quite High
Rheumatoid Arthritis 103 83.80 Quite High
Disease 12 62.20 Quite High
Apoptosis 12 48.60 Quite Low
Cancer 11 24.48 Low Low
Arthritis 5 21.96 Low Low
Leukemia 5 5.00 Very Low Very Low Very Low
Stress 5 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
For example, Decoy oligodeoxynucleotides (ODNs), short double stranded DNAs containing a consensus sequence for the NF-B binding sites, specifically block NF-B binding to the target genes and are effective in the down-regulation of pro-inflammatory cytokine gene expression in vitro [105].
Negative_regulation (block) of NF-B Binding (binding) of associated with inflammation and cytokine
1) Confidence 0.13 Published 2010 Journal PLoS ONE Section Body Doc Link PMC2855702 Disease Relevance 0.79 Pain Relevance 0.36

General Comments

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