INT306332

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Context Info
Confidence 0.45
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.09
Pain Relevance 0.19

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

plasma membrane (Cd14, Tlr4) signal transduction (Tlr4) extracellular space (Cd14)
intracellular (Tlr4) cytoplasm (Tlr4)
Anatomy Link Frequency
macrophages 2
Cd14 (Mus musculus)
Tlr4 (Mus musculus)
Pain Link Frequency Relevance Heat
cytokine 11 100.00 Very High Very High Very High
Inflammatory response 7 87.36 High High
Inflammation 27 50.00 Quite Low
chemokine 5 30.24 Quite Low
anesthesia 1 5.00 Very Low Very Low Very Low
isoflurane 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
INFLAMMATION 13 86.96 High High
Pneumonia 23 50.00 Quite Low
Targeted Disruption 2 5.00 Very Low Very Low Very Low
Cancer 1 5.00 Very Low Very Low Very Low
Bacterial Infection 1 5.00 Very Low Very Low Very Low
Hemorrhage 1 5.00 Very Low Very Low Very Low
Necrosis 1 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Published data on the contribution of CD14 to R-LPS- induced cytokine release are inconsistent: CD14 has been reported to be irrelevant for R-LPS-induced TNF production [14], whereas other investigations found that CD14 augmented R-LPS-induced cytokine secretion by macrophages [12], [21] as well as plasma TNF levels triggered by intravenous R-LPS [12].
CD14 Positive_regulation (augmented) of Localization (secretion) of LPS in macrophages associated with cytokine
1) Confidence 0.45 Published 2010 Journal PLoS ONE Section Body Doc Link PMC2855719 Disease Relevance 0.09 Pain Relevance 0.19

General Comments

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