INT306339

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Context Info
Confidence 0.53
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.27
Pain Relevance 0

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

nucleus (CRX, PAX6) cell differentiation (PAX6) nucleolus (PAX6)
DNA binding (PAX6) transcription factor binding (PAX6) cytoplasm (PAX6)
Anatomy Link Frequency
photoreceptor 1
CRX (Homo sapiens)
PAX6 (Homo sapiens)
Pain Link Frequency Relevance Heat
Central nervous system 1 5.00 Very Low Very Low Very Low
anesthesia 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Rod Or Cone Dystrophy 1 75.04 Quite High
Congenital Anomalies 7 74.80 Quite High
Aniridia 4 54.96 Quite High
Aphasia 1 24.60 Low Low
Cataract 4 22.68 Low Low
Corneal Opacity 8 22.00 Low Low
Ocular Toxicity (including Many Sub-types) 7 5.00 Very Low Very Low Very Low
Microphthalmia 3 5.00 Very Low Very Low Very Low
Ocular Hypertension 3 5.00 Very Low Very Low Very Low
Disease 2 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
To our knowledge, PAX6 protein can bind to the CRX promoter region in a selective manner [17], which supports its role as a direct transcriptional repressor of photoreceptor fate.
CRX Binding (bind) of PAX6 in photoreceptor
1) Confidence 0.53 Published 2010 Journal Molecular Vision Section Body Doc Link PMC2855731 Disease Relevance 0.27 Pain Relevance 0

General Comments

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