INT30645

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Context Info
Confidence 0.36
First Reported 1986
Last Reported 2010
Negated 2
Speculated 0
Reported most in Abstract
Documents 4
Total Number 4
Disease Relevance 0
Pain Relevance 3.07

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

nucleoplasm (RYBP) nucleus (RYBP) intracellular (RYBP)
DNA binding (RYBP) cytoplasm (RYBP)
Anatomy Link Frequency
bile 2
RYBP (Homo sapiens)
Pain Link Frequency Relevance Heat
Paracetamol 38 100.00 Very High Very High Very High
addiction 1 100.00 Very High Very High Very High
Bile 5 99.54 Very High Very High Very High
Disease Link Frequency Relevance Heat
Stress 1 5.00 Very Low Very Low Very Low
Weight Loss 1 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
In contrast, the excretion of APAP-NAC did not exhibit dependence on APAP-GSH concentration.
Regulation (dependence) of Localization (excretion) of APAP-NAC associated with addiction
1) Confidence 0.36 Published 1986 Journal J. Pharmacol. Exp. Ther. Section Abstract Doc Link 2871175 Disease Relevance 0 Pain Relevance 0.19
CFB pretreatment did not affect bile flow rate, nor did it affect the cumulative biliary excretion of APAP and its conjugated metabolites. 4.
Neg (nor) Regulation (affect) of Localization (excretion) of APAP in bile associated with paracetamol and bile
2) Confidence 0.24 Published 2000 Journal Xenobiotica Section Abstract Doc Link 11197064 Disease Relevance 0 Pain Relevance 1.02
Using principle component analysis, it was found that the viscosity of the matrix affects the pH-dependent release of APAP at pH 4.0 and pH 6.5.
Regulation (affects) of Localization (release) of APAP associated with paracetamol
3) Confidence 0.23 Published 2010 Journal Int J Pharm Section Abstract Doc Link 20472050 Disease Relevance 0 Pain Relevance 0.94
APAP release from the matrix tablets was not considerably influenced by changes in HPMC:HPC ratio or compression force.
Neg (not) Regulation (influenced) of Localization (release) of APAP associated with paracetamol
4) Confidence 0.10 Published 2004 Journal Int J Pharm Section Abstract Doc Link 15019065 Disease Relevance 0 Pain Relevance 0.93

General Comments

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