INT306469

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Context Info
Confidence 0.40
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 2
Disease Relevance 1.72
Pain Relevance 0.29

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

extracellular space (MBL2) extracellular region (MBL2)
MBL2 (Homo sapiens)
Pain Link Frequency Relevance Heat
Inflammation 24 98.24 Very High Very High Very High
cytokine 10 95.56 Very High Very High Very High
chemokine 2 51.04 Quite High
Pain 2 5.00 Very Low Very Low Very Low
Antihistamine 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
INFLAMMATION 24 98.24 Very High Very High Very High
Skin Infection 18 95.20 Very High Very High Very High
Staphylococcus Infection 6 93.84 High High
Dermatological Disease 18 88.84 High High
Disease 34 88.40 High High
Syndrome 2 85.12 High High
Ulcers 2 83.44 Quite High
Recurrence 4 75.84 Quite High
Apoptosis 12 74.92 Quite High
Infection 26 74.72 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Genotype analysis revealed specific point mutations in the MBL2 promoter in all 6 patients and a variant MASP-2 gene in one patient.
Negative_regulation (gene) of Gene_expression (promoter) of MBL2
1) Confidence 0.40 Published 2010 Journal Clin Mol Allergy Section Abstract Doc Link PMC2856528 Disease Relevance 1.31 Pain Relevance 0.08
Defective MBL production is regarded as the most common immune deficiency in the general population, affecting approximately 5-7% of individuals [2], although some descriptions have delineated higher figures among Caucasians (up to 30%) [3].
Negative_regulation (Defective) of Gene_expression (production) of MBL
2) Confidence 0.36 Published 2010 Journal Clin Mol Allergy Section Body Doc Link PMC2856528 Disease Relevance 0.42 Pain Relevance 0.21

General Comments

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