INT306500

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Context Info
Confidence 0.22
First Reported 2010
Last Reported 2010
Negated 1
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.13
Pain Relevance 0

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytoplasm (Clu, Esr1) nucleus (Clu, Esr1) mitochondrion (Clu)
endoplasmic reticulum (Clu) enzyme binding (Esr1) DNA binding (Esr1)
Clu (Mus musculus)
Esr1 (Mus musculus)
Pain Link Frequency Relevance Heat
cytokine 3 5.00 Very Low Very Low Very Low
anesthesia 1 5.00 Very Low Very Low Very Low
imagery 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Apoptosis 22 76.24 Quite High
Cancer 29 5.00 Very Low Very Low Very Low
Breast Cancer 12 5.00 Very Low Very Low Very Low
Death 9 5.00 Very Low Very Low Very Low
Reprotox - General 1 4 5.00 Very Low Very Low Very Low
Stress 4 5.00 Very Low Very Low Very Low
Metastasis 2 5.00 Very Low Very Low Very Low
Embolism 2 5.00 Very Low Very Low Very Low
Carcinoma 2 5.00 Very Low Very Low Very Low
Body Weight 1 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
While the basal level of pS2 mRNA is elevated in untreated MCF-7CLU cells relative to the parental cell line, the estrogen induced expression of pS2 mRNA, and the responsiveness to tamoxifen is essentially equivalent in the parental and MCF-7CLU cell lines, indicating that clusterin over expression has not significantly altered the ability of the estrogen receptor to transactivate known target genes.
clusterin Neg (not) Regulation (altered) of estrogen receptor
1) Confidence 0.22 Published 2010 Journal BMC Cancer Section Body Doc Link PMC2856549 Disease Relevance 0.13 Pain Relevance 0

General Comments

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