INT306521

From wiki-pain
Jump to: navigation, search
Context Info
Confidence 0.69
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 4
Disease Relevance 4.13
Pain Relevance 0.05

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

Golgi apparatus (Htt) endoplasmic reticulum (Htt) mitochondrion organization (Htt)
embryo development (Htt) protein complex (Htt) cytoplasm (Htt)
Anatomy Link Frequency
brain 1
striatum 1
cortex 1
Htt (Mus musculus)
Pain Link Frequency Relevance Heat
Neurotransmitter 20 94.00 High High
cerebral cortex 4 34.60 Quite Low
Hippocampus 4 33.92 Quite Low
Dopamine 12 5.00 Very Low Very Low Very Low
monoamine 4 5.00 Very Low Very Low Very Low
Pain 4 5.00 Very Low Very Low Very Low
Serotonin 4 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Disease 220 100.00 Very High Very High Very High
Targeted Disruption 40 87.12 High High
Syndrome 4 86.16 High High
Frailty 8 84.88 Quite High
Spinocerebellar Ataxia Type 2 16 84.04 Quite High
Obesity 8 5.00 Very Low Very Low Very Low
Pain 4 5.00 Very Low Very Low Very Low
Neurodegenerative Disease 4 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Notably, in HD, striking somatic expansion of the HD CAG repeat occurs in the striatum and cortex, brain regions that are major targets of the pathogenic process.
Transcription (expansion) of HD in brain associated with disease
1) Confidence 0.69 Published 2010 Journal BMC Syst Biol Section Body Doc Link PMC2856555 Disease Relevance 1.21 Pain Relevance 0
In addition, Hdh expression levels did not correlate with instability index in tissues (data not shown), confirming observations that although transcription through expanded repeats may be important in somatic instability [31], tissue-specific patterns are not reflected in the steady state levels of Hdh mRNA.
Transcription (levels) of Hdh
2) Confidence 0.53 Published 2010 Journal BMC Syst Biol Section Body Doc Link PMC2856555 Disease Relevance 0.50 Pain Relevance 0.05
Notably, in HD, striking somatic expansion of the HD CAG repeat occurs in the striatum and cortex, brain regions that are major targets of the pathogenic process.
Transcription (expansion) of HD in cortex associated with disease
3) Confidence 0.23 Published 2010 Journal BMC Syst Biol Section Body Doc Link PMC2856555 Disease Relevance 1.21 Pain Relevance 0
Notably, in HD, striking somatic expansion of the HD CAG repeat occurs in the striatum and cortex, brain regions that are major targets of the pathogenic process.
Transcription (expansion) of HD in striatum associated with disease
4) Confidence 0.23 Published 2010 Journal BMC Syst Biol Section Body Doc Link PMC2856555 Disease Relevance 1.21 Pain Relevance 0

General Comments

This test has worked.

Personal tools
Namespaces

Variants
Actions
Navigation
Toolbox