INT306527

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Context Info
Confidence 0.20
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.82
Pain Relevance 0.04

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytoplasm (Htt, Aifm1) cytosol (Htt, Aifm1) nucleus (Htt, Aifm1)
mitochondrion (Aifm1) Golgi apparatus (Htt) endoplasmic reticulum (Htt)
Anatomy Link Frequency
cerebellar granule cell 1
Htt (Mus musculus)
Aifm1 (Mus musculus)
Pain Link Frequency Relevance Heat
Dopamine 3 83.44 Quite High
Neurotransmitter 5 5.00 Very Low Very Low Very Low
cerebral cortex 1 5.00 Very Low Very Low Very Low
monoamine 1 5.00 Very Low Very Low Very Low
Pain 1 5.00 Very Low Very Low Very Low
Hippocampus 1 5.00 Very Low Very Low Very Low
Serotonin 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Disease 55 94.00 High High
Neurodegenerative Disease 1 78.08 Quite High
Targeted Disruption 10 45.28 Quite Low
Spinocerebellar Ataxia Type 2 4 5.00 Very Low Very Low Very Low
Obesity 2 5.00 Very Low Very Low Very Low
Frailty 2 5.00 Very Low Very Low Very Low
Pain 1 5.00 Very Low Very Low Very Low
Syndrome 1 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
We also tested whether inducing neurodegeneration in the cerebellum, a normally stable tissue, would cause instability in the cerebellum by crossing HdhQ111 mice to Harlequin (Hq) mice, a model of cerebellar granule cell degeneration [23].
HdhQ111 Binding (crossing) of Hq in cerebellar granule cell
1) Confidence 0.20 Published 2010 Journal BMC Syst Biol Section Body Doc Link PMC2856555 Disease Relevance 0.82 Pain Relevance 0.04

General Comments

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