INT306693

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Context Info
Confidence 0.10
First Reported 2010
Last Reported 2010
Negated 0
Speculated 1
Reported most in Body
Documents 1
Total Number 3
Disease Relevance 0.06
Pain Relevance 0.39

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytoplasm (Prkca, Nav1) cell differentiation (Nav1) mitochondrion (Prkca)
endoplasmic reticulum (Prkca) enzyme binding (Prkca) protein complex (Prkca)
Anatomy Link Frequency
sensory neurons 2
Prkca (Mus musculus)
Nav1 (Mus musculus)
Pain Link Frequency Relevance Heat
tetrodotoxin 45 88.72 High High
addiction 27 82.64 Quite High
Action potential 12 52.64 Quite High
dorsal root ganglion 27 31.76 Quite Low
Inflammation 12 5.00 Very Low Very Low Very Low
sodium channel 6 5.00 Very Low Very Low Very Low
Pain 6 5.00 Very Low Very Low Very Low
Hyperalgesia 6 5.00 Very Low Very Low Very Low
unmyelinated 6 5.00 Very Low Very Low Very Low
Spinal cord 3 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Targeted Disruption 3 61.80 Quite High
Ganglion Cysts 30 50.00 Quite Low
Nociception 12 19.24 Low Low
INFLAMMATION 12 5.00 Very Low Very Low Very Low
Pain 9 5.00 Very Low Very Low Very Low
Hyperalgesia 6 5.00 Very Low Very Low Very Low
Dislocations 3 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Modification of the spontaneous augmentation of NaV1.9 by PKA and PKC
PKC Regulation (Modification) of Positive_regulation (augmentation) of NaV1
1) Confidence 0.10 Published 2010 Journal Marine Drugs Section Body Doc Link PMC2857352 Disease Relevance 0.06 Pain Relevance 0.33
However, the effects of PKA and PKC on the spontaneous augmentation of NaV1.9 in sensory neurons have not been investigated.
PKC Spec (investigated) Regulation (effects) of Positive_regulation (augmentation) of NaV1 in sensory neurons
2) Confidence 0.09 Published 2010 Journal Marine Drugs Section Body Doc Link PMC2857352 Disease Relevance 0 Pain Relevance 0.03
Next, we focused on the effect of PKC on the spontaneous augmentation of NaV1.9.
PKC Regulation (effect) of Positive_regulation (augmentation) of NaV1
3) Confidence 0.09 Published 2010 Journal Marine Drugs Section Body Doc Link PMC2857352 Disease Relevance 0 Pain Relevance 0.04

General Comments

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