INT306772

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Context Info
Confidence 0.08
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.06
Pain Relevance 0.04

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

oxidoreductase activity (Cyp1a2) endoplasmic reticulum (Cyp1a2) enzyme binding (Cyp1a2)
Anatomy Link Frequency
plasma 2
Cyp1a2 (Mus musculus)
Pain Link Frequency Relevance Heat
Bioavailability 2 77.76 Quite High
Dopamine 23 5.00 Very Low Very Low Very Low
agonist 6 5.00 Very Low Very Low Very Low
Central nervous system 5 5.00 Very Low Very Low Very Low
headache 4 5.00 Very Low Very Low Very Low
antagonist 3 5.00 Very Low Very Low Very Low
positron emission tomography 3 5.00 Very Low Very Low Very Low
Substantia nigra 2 5.00 Very Low Very Low Very Low
dopamine receptor 2 5.00 Very Low Very Low Very Low
imagery 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Restless Legs Syndrome 89 56.88 Quite High
Sleep Disorders 13 50.00 Quite Low
Nicotine Addiction 1 48.32 Quite Low
Vomiting 10 5.00 Very Low Very Low Very Low
Movement Disorders 9 5.00 Very Low Very Low Very Low
Disease 6 5.00 Very Low Very Low Very Low
Anaemia 5 5.00 Very Low Very Low Very Low
Headache 4 5.00 Very Low Very Low Very Low
Dyskinesias 3 5.00 Very Low Very Low Very Low
Dizziness 2 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Ciprofloxacine, an inhibitor of CYP1A2 did increase plasma levels of ropinirole when these two drugs were co-administered.
Positive_regulation (increase) of Negative_regulation (inhibitor) of CYP1A2 in plasma
1) Confidence 0.08 Published 2010 Journal Therapeutics and Clinical Risk Management Section Body Doc Link PMC2857615 Disease Relevance 0.06 Pain Relevance 0.04

General Comments

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