INT306829

Context Info Confidence 0.09 First Reported 2010 Last Reported 2010 Negated 0 Speculated 0 Reported most in Body Documents 1 Total Number 1 Disease Relevance 0.06 Pain Relevance 0

nucleoplasm (E2F2, RBL1) nucleus (E2F2, RBL1) transcription factor binding (E2F2, RBL1) DNA binding (E2F2)

E2F2 (Homo sapiens) RBL1 (Homo sapiens)

Pain Link Frequency Relevance Heat qutenza 130 50.00 Inflammation 1 5.00 Pain 1 5.00

Disease Link Frequency Relevance Heat Small Cell Lung Cancer 63 55.36 Breast Cancer 2 30.24 Reprotox - General 1 4 10.08 Squamous Cell Carcinoma 1 9.04 Cancer 42 5.00 Lung Cancer 10 5.00 Apoptosis 6 5.00 Disease 3 5.00 Metastasis 2 5.00 Weight Loss 2 5.00

Sentences Mentioned In

Key:

Protein

Mutation

Event

Anatomy

Negation

Speculation

Pain term

Disease term

Thus, quiescent cells contain high levels of E2F proteins bound to Rb, p130 and p107.

E2F Binding (bound) of p107

1) Confidence 0.09 Published 2010 Journal PLoS ONE Section Body Doc Link PMC2857654 Disease Relevance 0.06 Pain Relevance 0

General Comments

This test has worked.