INT306836

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Context Info
Confidence 0.19
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 2
Disease Relevance 1.28
Pain Relevance 1.88

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytosol (CDC6) nucleoplasm (CDC6) mitosis (CDC6)
nucleus (CDC6) cell division (CDC6) cytoplasm (CDC6)
CDC6 (Homo sapiens)
Pain Link Frequency Relevance Heat
qutenza 260 99.98 Very High Very High Very High
Inflammation 2 5.00 Very Low Very Low Very Low
Pain 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Small Cell Lung Cancer 126 96.08 Very High Very High Very High
Cancer 84 88.24 High High
Lung Cancer 20 58.40 Quite High
Body Weight 4 56.48 Quite High
Apoptosis 12 5.00 Very Low Very Low Very Low
Reprotox - General 1 8 5.00 Very Low Very Low Very Low
Disease 6 5.00 Very Low Very Low Very Low
Metastasis 4 5.00 Very Low Very Low Very Low
Weight Loss 4 5.00 Very Low Very Low Very Low
Breast Cancer 4 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Taken together, capsaicin suppressed the expression of cyclin E, TS, cdc25A and cdc6 both at mRNA and protein levels in human SCLCs.


Negative_regulation (suppressed) of Gene_expression (expression) of cdc6 associated with qutenza
1) Confidence 0.19 Published 2010 Journal PLoS ONE Section Body Doc Link PMC2857654 Disease Relevance 0.56 Pain Relevance 0.93
Furthermore, capsaicin-induced growth arrest was associated with a decrease in the expression of the E2F target genes cyclin E, TS, cdc25A and cdc6.
Negative_regulation (decrease) of Gene_expression (expression) of cdc6 associated with qutenza
2) Confidence 0.19 Published 2010 Journal PLoS ONE Section Body Doc Link PMC2857654 Disease Relevance 0.72 Pain Relevance 0.95

General Comments

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