INT306846

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Context Info
Confidence 0.24
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.65
Pain Relevance 0.94

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

nucleoplasm (E2F3) nucleus (E2F3) DNA binding (E2F3)
E2F3 (Homo sapiens)
Pain Link Frequency Relevance Heat
qutenza 130 99.98 Very High Very High Very High
Inflammation 1 5.00 Very Low Very Low Very Low
Pain 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Small Cell Lung Cancer 63 99.04 Very High Very High Very High
Cancer 42 73.68 Quite High
Lung Cancer 10 51.16 Quite High
Apoptosis 6 5.00 Very Low Very Low Very Low
Reprotox - General 1 4 5.00 Very Low Very Low Very Low
Disease 3 5.00 Very Low Very Low Very Low
Metastasis 2 5.00 Very Low Very Low Very Low
Weight Loss 2 5.00 Very Low Very Low Very Low
Breast Cancer 2 5.00 Very Low Very Low Very Low
Non-small-cell Lung Cancer 2 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Finally, chromatin IP (ChIP) analysis of human SCLC cells demonstrated that treatment of capsaicin decreased the recruitment of activator E2Fs, namely E2F2 and E2F3, to proliferative promoters like cyclin E, TS, cdc25A and cdc6.
Negative_regulation (decreased) of E2F3 Binding (recruitment) of associated with qutenza and small cell lung cancer
1) Confidence 0.24 Published 2010 Journal PLoS ONE Section Body Doc Link PMC2857654 Disease Relevance 0.65 Pain Relevance 0.94

General Comments

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