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Context Info
Confidence 0.17
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 1.06
Pain Relevance 0.71

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytosol (CDK4) nucleoplasm (CDK4) signal transduction (CDK4)
nucleolus (CDK4) nucleus (CDK4) cell cycle (CDK4)
CDK4 (Homo sapiens)
Pain Link Frequency Relevance Heat
qutenza 130 98.50 Very High Very High Very High
Inflammation 1 44.32 Quite Low
Pain 1 43.64 Quite Low
Disease Link Frequency Relevance Heat
Breast Cancer 2 99.20 Very High Very High Very High
Reprotox - General 1 4 83.16 Quite High
Squamous Cell Carcinoma 1 82.12 Quite High
Cancer 42 77.36 Quite High
Apoptosis 6 74.56 Quite High
Stomach Cancer 2 65.68 Quite High
Anaplastic Astrocytoma 1 64.24 Quite High
Esophageal Cancer 1 63.72 Quite High
Leukemia 1 62.84 Quite High
Non-small-cell Lung Cancer 2 62.12 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Capsaicin-induced G1 arrest is correlated with the suppression of cyclin D1 levels, inhibition of cdk4 activity and Rb phosphorylation in endothelial and breast cancer cells [21], [22].
Negative_regulation (inhibition) of Phosphorylation (phosphorylation) of cdk4 associated with qutenza and breast cancer
1) Confidence 0.17 Published 2010 Journal PLoS ONE Section Body Doc Link PMC2857654 Disease Relevance 1.06 Pain Relevance 0.71

General Comments

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