INT306947

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Context Info
Confidence 0.13
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 2
Disease Relevance 1.41
Pain Relevance 0

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

small molecule metabolic process (NAMPT, INS) cell-cell signaling (NAMPT, INS) transferase activity, transferring glycosyl groups (NAMPT)
carbohydrate metabolic process (INS) cytoplasm (NAMPT) cytosol (NAMPT)
Anatomy Link Frequency
myocytes 1
adipocytes 1
NAMPT (Homo sapiens)
INS (Homo sapiens)
Pain Link Frequency Relevance Heat
Inflammation 18 35.04 Quite Low
Angina 4 5.00 Very Low Very Low Very Low
cytokine 2 5.00 Very Low Very Low Very Low
tolerance 2 5.00 Very Low Very Low Very Low
Somatostatin 2 5.00 Very Low Very Low Very Low
ischemia 2 5.00 Very Low Very Low Very Low
Inflammatory response 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Obesity 74 98.48 Very High Very High Very High
Fetal Death 2 87.64 High High
Targeted Disruption 2 83.84 Quite High
Diabetes Mellitus 80 70.92 Quite High
Weight Gain 2 70.20 Quite High
Increased Venous Pressure Under Development 6 50.00 Quite Low
INFLAMMATION 20 35.04 Quite Low
Atherosclerosis 20 5.00 Very Low Very Low Very Low
Coronary Artery Disease 14 5.00 Very Low Very Low Very Low
Metabolic Syndrome 12 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
In addition, the study has demonstrated insulin-mimetic effects of visfatin such as: increased glucose uptake in adipocytes and myocytes, suppression of hepatic glucose release, stimulated triglyceride accumulation, and increase in its synthesis in pre-adipocytes.
visfatin Regulation (effects) of insulin in adipocytes associated with obesity
1) Confidence 0.13 Published 2010 Journal Diabetol Metab Syndr Section Body Doc Link PMC2857825 Disease Relevance 0.70 Pain Relevance 0
In addition, the study has demonstrated insulin-mimetic effects of visfatin such as: increased glucose uptake in adipocytes and myocytes, suppression of hepatic glucose release, stimulated triglyceride accumulation, and increase in its synthesis in pre-adipocytes.
visfatin Regulation (effects) of insulin in myocytes associated with obesity
2) Confidence 0.05 Published 2010 Journal Diabetol Metab Syndr Section Body Doc Link PMC2857825 Disease Relevance 0.70 Pain Relevance 0

General Comments

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