INT30701

From wiki-pain
Jump to: navigation, search
Context Info
Confidence 0.27
First Reported 1986
Last Reported 2010
Negated 0
Speculated 0
Reported most in Abstract
Documents 4
Total Number 4
Disease Relevance 0.31
Pain Relevance 2.79

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cell death (PDYN) extracellular region (PDYN) plasma membrane (PDYN)
Anatomy Link Frequency
central nervous system 2
PDYN (Homo sapiens)
Pain Link Frequency Relevance Heat
Enkephalin 15 100.00 Very High Very High Very High
Dynorphin 3 100.00 Very High Very High Very High
Central nervous system 1 99.68 Very High Very High Very High
Antinociceptive 6 99.12 Very High Very High Very High
Paracetamol 2 95.68 Very High Very High Very High
analgesia 6 94.00 High High
antagonist 17 93.12 High High
opioid receptor 29 92.64 High High
Endogenous opioid 10 91.84 High High
antinociception 16 88.56 High High
Disease Link Frequency Relevance Heat
INFLAMMATION 5 88.20 High High
Hyperalgesia 1 86.40 High High
Inflammatory Pain 3 54.72 Quite High
Nociception 5 49.12 Quite Low
Pain 7 44.08 Quite Low
Overdose 1 5.00 Very Low Very Low Very Low
Congenital Anomalies 1 5.00 Very Low Very Low Very Low
Aging 1 5.00 Very Low Very Low Very Low
Increased Venous Pressure Under Development 1 5.00 Very Low Very Low Very Low
Osteoarthritis 1 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
The amount of protection given by these substances seems to be sufficient to play a significant role in controlling the physiological levels of leu-enkephalin released into the bloodstream.
Regulation (controlling) of Localization (released) of leu-enkephalin associated with enkephalin
1) Confidence 0.27 Published 1986 Journal Comp. Biochem. Physiol. C, Comp. Pharmacol. Toxicol. Section Abstract Doc Link 2871993 Disease Relevance 0 Pain Relevance 0.35
The amount of protection given by these substances seems to be sufficient to play a significant role in controlling the physiological levels of leu-enkephalin released into the bloodstream.
Regulation (role) of Localization (released) of leu-enkephalin associated with enkephalin
2) Confidence 0.27 Published 1986 Journal Comp. Biochem. Physiol. C, Comp. Pharmacol. Toxicol. Section Abstract Doc Link 2871993 Disease Relevance 0 Pain Relevance 0.35
Thus, some COX inhibitors may exert their antinociceptive effect also through the opioidergic system modulating dynorphin release in the central nervous system [21].
Regulation (modulating) of Localization (release) of dynorphin in central nervous system associated with dynorphin, central nervous system and antinociceptive
3) Confidence 0.26 Published 2010 Journal The Korean Journal of Pain Section Body Doc Link PMC3000619 Disease Relevance 0.31 Pain Relevance 1.80
Due to the use of thiolated polymers also a controlled drug release for leu-enkephalin was guaranteed over a time period for more than 24 h.
Regulation (controlled) of Localization (release) of leu-enkephalin associated with enkephalin
4) Confidence 0.25 Published 2003 Journal Int J Pharm Section Abstract Doc Link 12550789 Disease Relevance 0 Pain Relevance 0.29

General Comments

This test has worked.

Personal tools
Namespaces

Variants
Actions
Navigation
Toolbox