INT307018

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Context Info
Confidence 0.05
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 2
Disease Relevance 0.83
Pain Relevance 0.29

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

Anatomy Link Frequency
NK cells 4
MT1JP (Homo sapiens)
CD69 (Homo sapiens)
Pain Link Frequency Relevance Heat
Inflammation 72 95.40 Very High Very High Very High
Inflammatory mediators 4 93.92 High High
cytokine 66 86.96 High High
Inflammatory response 6 5.00 Very Low Very Low Very Low
depression 4 5.00 Very Low Very Low Very Low
Bile 4 5.00 Very Low Very Low Very Low
tolerance 4 5.00 Very Low Very Low Very Low
Crohn's disease 4 5.00 Very Low Very Low Very Low
spastic colon 2 5.00 Very Low Very Low Very Low
Arthritis 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Cancer 24 95.68 Very High Very High Very High
INFLAMMATION 78 95.40 Very High Very High Very High
Bacterial Respiratory Disease 2 88.92 High High
Stress 4 77.48 Quite High
Sprains And Strains 12 52.16 Quite High
Disease 10 5.00 Very Low Very Low Very Low
Inflammatory Bowel Disease 6 5.00 Very Low Very Low Very Low
Arthritis 4 5.00 Very Low Very Low Very Low
Depression 4 5.00 Very Low Very Low Very Low
Obesity 4 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Both MTB and CW induced the expression of the CD69 activation marker on human CD3- CD56+ NK cells, and enhanced the expression of CD107a when exposed to K562 tumor cells in vitro.
MTB Positive_regulation (induced) of Gene_expression (expression) of CD69 in NK cells associated with cancer
1) Confidence 0.05 Published 2010 Journal BMC Immunol Section Abstract Doc Link PMC2858026 Disease Relevance 0.58 Pain Relevance 0.25
Both MTB and CW showed a clear dose-dependent induction of the expression of CD69 on NK cells (Figure 4A).
MTB Positive_regulation (induction) of Gene_expression (expression) of CD69 in NK cells
2) Confidence 0.05 Published 2010 Journal BMC Immunol Section Body Doc Link PMC2858026 Disease Relevance 0.25 Pain Relevance 0.03

General Comments

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