INT307044

Context Info Confidence 0.01 First Reported 2010 Last Reported 2010 Negated 1 Speculated 0 Reported most in Body Documents 1 Total Number 1 Disease Relevance 0 Pain Relevance 0.75

cytosol (Casp3) peptidase activity (Casp3) mitochondrion (Casp3) nucleus (Casp3) intracellular (Casp3) cytoplasm (Casp3)

Tmie (Mus musculus) Casp3 (Mus musculus)

Pain Link Frequency Relevance Heat antagonist 10 99.98 Cannabinoid 47 99.48 Dopamine 24 97.40 dopamine receptor 1 65.32 agonist 24 62.56 Cannabinoid receptor 8 46.96 Serotonin 15 5.00 Hippocampus 7 5.00 monoamine 5 5.00 cannabis 5 5.00

Disease Link Frequency Relevance Heat Anxiety Disorder 3 15.20 Targeted Disruption 3 13.20 Recurrence 3 5.00 Stress 2 5.00 Sprains And Strains 1 5.00 Urological Neuroanatomy 1 5.00 Injury 1 5.00 Psychosis 1 5.00

Sentences Mentioned In

Key:

Protein

Mutation

Event

Anatomy

Negation

Speculation

Pain term

Disease term

The cannabinoid-selective CB1 antagonist SR 141716 did not affect the CPP or reinstatement of the preference induced by 5 mg/kg of MDMA when administered alone or with WIN.

SR Neg (not) Regulation (affect) of CPP associated with antagonist and cannabinoid

1) Confidence 0.01 Published 2010 Journal Behav Brain Funct Section Body Doc Link PMC2858089 Disease Relevance 0 Pain Relevance 0.75

General Comments

This test has worked.