INT307047

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Context Info
Confidence 0.11
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 3
Disease Relevance 0.06
Pain Relevance 1.03

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytoplasm (Foxm1, Casp3) nucleus (Foxm1, Casp3) mitochondrion (Casp3)
intracellular (Casp3) embryo development (Foxm1) DNA binding (Foxm1)
Foxm1 (Mus musculus)
Casp3 (Mus musculus)
Pain Link Frequency Relevance Heat
agonist 72 99.98 Very High Very High Very High
Cannabinoid 141 93.64 High High
Serotonin 45 88.16 High High
Dopamine 72 86.96 High High
antagonist 30 71.44 Quite High
Neurotransmitter 6 70.04 Quite High
Hippocampus 21 59.04 Quite High
Cannabinoid receptor 24 5.00 Very Low Very Low Very Low
monoamine 15 5.00 Very Low Very Low Very Low
cannabis 15 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Recurrence 9 56.68 Quite High
Targeted Disruption 9 5.00 Very Low Very Low Very Low
Anxiety Disorder 9 5.00 Very Low Very Low Very Low
Stress 6 5.00 Very Low Very Low Very Low
Sprains And Strains 3 5.00 Very Low Very Low Very Low
Urological Neuroanatomy 3 5.00 Very Low Very Low Very Low
Injury 3 5.00 Very Low Very Low Very Low
Psychosis 3 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
In addition, the CB1 agonist WIN also induced CPP with the highest dose employed (0.5 mg/kg).
WIN Positive_regulation (induced) of CPP associated with agonist
1) Confidence 0.11 Published 2010 Journal Behav Brain Funct Section Body Doc Link PMC2858089 Disease Relevance 0 Pain Relevance 0.47
The highest dose of WIN (0.5 mg/kg) also induced CPP.
WIN Positive_regulation (induced) of CPP
2) Confidence 0.09 Published 2010 Journal Behav Brain Funct Section Body Doc Link PMC2858089 Disease Relevance 0 Pain Relevance 0.06
The highest WIN dose (0.5 mg/kg), which in itself induced CPP, diminished preference when administered with an effective dose of MDMA (2.5 and 5 mg/kg).
WIN Positive_regulation (induced) of CPP
3) Confidence 0.07 Published 2010 Journal Behav Brain Funct Section Body Doc Link PMC2858089 Disease Relevance 0.06 Pain Relevance 0.50

General Comments

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